Basal Values of Biochemical and Hematological Parameters in Elite Athletes
The purpose of this study was to show how continuous exercise affects the basal values of biochemical and hematological parameters in elite athletes. A total of 14,010 samples (male = 8452 and female = 5558 (March 2011-March 2020)) from 3588 elite athletes (male = 2258 and female = 1330, mean age 24...
Gespeichert in:
| Veröffentlicht in: | International journal of environmental research and public health 2022-03, Vol.19 (5), p.3059 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 5 |
| container_start_page | 3059 |
| container_title | International journal of environmental research and public health |
| container_volume | 19 |
| creator | Díaz Martínez, Angel Enrique Alcaide Martín, María José González-Gross, Marcela |
| description | The purpose of this study was to show how continuous exercise affects the basal values of biochemical and hematological parameters in elite athletes. A total of 14,010 samples (male = 8452 and female = 5558 (March 2011-March 2020)) from 3588 elite athletes (male = 2258 and female = 1330, mean age 24.9 ± 6.9 vs. 24.1 ± 5.5 years, respectively) from 32 sport modalities, were studied over 9 years to check the variation of basal biochemical and hematological parameter values. There were differences seen in the basal values of creatine kinase (CK), urea, creatinine, aspartate transaminase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), potassium, total bilirubin, and eosinophil percentage compared to reference population data. However, other analytes showed narrow ranges of variation like glucose, total protein, albumin, sodium, hemoglobin, mean cell volume (MCV), and platelet count. Exercise produces changes in biochemical and hematological basal values of athletes compared to the general population, with the greatest variation in CK, but AST, ALT, LDH, potassium, and total bilirubin (TBil) show high values in serum, only with a wider distribution of values. The data here reflects the effect of exercise on biochemical and hematological parameter baseline ranges in elite athletes. As clinical laboratories use reference intervals to validate clinical reports, these "pseudo" reference intervals should be used when validating laboratory reports. |
| doi_str_mv | 10.3390/ijerph19053059 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8910271</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2638713935</sourcerecordid><originalsourceid>FETCH-LOGICAL-c418t-819b02a489879fa375f41b7c910151d07cbd20c06114bc12168d068b641984953</originalsourceid><addsrcrecordid>eNpdkUtP3DAUha2qqDy3XVaRuulm4N7YcexNJRgNLyHBAthajuMwHjnx1M4g9d_jYWAErGwdfz73Hh1CfiIcUyrhxC1sXM5RQkWhkt_IHnIOE8YBv3-475L9lBYAVDAuf5BdWpU11BXskesznbQvHrVf2VSErjhzwcxt70xW9dAWl7bXY_Dh6VW501H3drQxFW4oZt6Ntjgd5z5L6ZDsdNone_R2HpCH89n99HJyc3txNT29mRiGYpwIlA2UmgkpatlpWlcdw6Y2EgErbKE2TVuCAY7IGoMlctECFw1nKAWTFT0gfze-y1XT29bYYYzaq2V0vY7_VdBOfX4Z3Fw9hWcl8oiyxmzw580ghn859qh6l4z1Xg82rJIqORUZk3Q96_cXdBFWccjx1lTNBTIpM3W8oUwMKUXbbZdBUOua1Oea8odfHyNs8fde6AvZho1W</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2637681499</pqid></control><display><type>article</type><title>Basal Values of Biochemical and Hematological Parameters in Elite Athletes</title><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><source>PubMed Central Open Access</source><creator>Díaz Martínez, Angel Enrique ; Alcaide Martín, María José ; González-Gross, Marcela</creator><creatorcontrib>Díaz Martínez, Angel Enrique ; Alcaide Martín, María José ; González-Gross, Marcela</creatorcontrib><description>The purpose of this study was to show how continuous exercise affects the basal values of biochemical and hematological parameters in elite athletes. A total of 14,010 samples (male = 8452 and female = 5558 (March 2011-March 2020)) from 3588 elite athletes (male = 2258 and female = 1330, mean age 24.9 ± 6.9 vs. 24.1 ± 5.5 years, respectively) from 32 sport modalities, were studied over 9 years to check the variation of basal biochemical and hematological parameter values. There were differences seen in the basal values of creatine kinase (CK), urea, creatinine, aspartate transaminase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), potassium, total bilirubin, and eosinophil percentage compared to reference population data. However, other analytes showed narrow ranges of variation like glucose, total protein, albumin, sodium, hemoglobin, mean cell volume (MCV), and platelet count. Exercise produces changes in biochemical and hematological basal values of athletes compared to the general population, with the greatest variation in CK, but AST, ALT, LDH, potassium, and total bilirubin (TBil) show high values in serum, only with a wider distribution of values. The data here reflects the effect of exercise on biochemical and hematological parameter baseline ranges in elite athletes. As clinical laboratories use reference intervals to validate clinical reports, these "pseudo" reference intervals should be used when validating laboratory reports.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph19053059</identifier><identifier>PMID: 35270750</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Adolescent ; Adult ; Alanine ; Alanine Transaminase ; Albumins ; Aspartate Aminotransferases ; Aspartate transaminase ; Athletes ; Bicycling ; Bilirubin ; Biochemistry ; Biomarkers ; Cell size ; Creatine ; Creatine Kinase ; Creatinine ; Exercise ; Female ; Football ; Hematology ; Hemoglobin ; Humans ; L-Lactate Dehydrogenase ; Lactate dehydrogenase ; Lactic acid ; Leukocytes (eosinophilic) ; Male ; Marathons ; Medical laboratories ; Physical fitness ; Physiology ; Population ; Potassium ; Reference Values ; Rugby ; Running ; Sports medicine ; Transaminase ; Urea ; Variation ; Young Adult</subject><ispartof>International journal of environmental research and public health, 2022-03, Vol.19 (5), p.3059</ispartof><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 by the authors. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c418t-819b02a489879fa375f41b7c910151d07cbd20c06114bc12168d068b641984953</citedby><cites>FETCH-LOGICAL-c418t-819b02a489879fa375f41b7c910151d07cbd20c06114bc12168d068b641984953</cites><orcidid>0000-0002-6215-0093 ; 0000-0001-7757-3235 ; 0000-0003-3472-8107</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910271/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910271/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35270750$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Díaz Martínez, Angel Enrique</creatorcontrib><creatorcontrib>Alcaide Martín, María José</creatorcontrib><creatorcontrib>González-Gross, Marcela</creatorcontrib><title>Basal Values of Biochemical and Hematological Parameters in Elite Athletes</title><title>International journal of environmental research and public health</title><addtitle>Int J Environ Res Public Health</addtitle><description>The purpose of this study was to show how continuous exercise affects the basal values of biochemical and hematological parameters in elite athletes. A total of 14,010 samples (male = 8452 and female = 5558 (March 2011-March 2020)) from 3588 elite athletes (male = 2258 and female = 1330, mean age 24.9 ± 6.9 vs. 24.1 ± 5.5 years, respectively) from 32 sport modalities, were studied over 9 years to check the variation of basal biochemical and hematological parameter values. There were differences seen in the basal values of creatine kinase (CK), urea, creatinine, aspartate transaminase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), potassium, total bilirubin, and eosinophil percentage compared to reference population data. However, other analytes showed narrow ranges of variation like glucose, total protein, albumin, sodium, hemoglobin, mean cell volume (MCV), and platelet count. Exercise produces changes in biochemical and hematological basal values of athletes compared to the general population, with the greatest variation in CK, but AST, ALT, LDH, potassium, and total bilirubin (TBil) show high values in serum, only with a wider distribution of values. The data here reflects the effect of exercise on biochemical and hematological parameter baseline ranges in elite athletes. As clinical laboratories use reference intervals to validate clinical reports, these "pseudo" reference intervals should be used when validating laboratory reports.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Alanine</subject><subject>Alanine Transaminase</subject><subject>Albumins</subject><subject>Aspartate Aminotransferases</subject><subject>Aspartate transaminase</subject><subject>Athletes</subject><subject>Bicycling</subject><subject>Bilirubin</subject><subject>Biochemistry</subject><subject>Biomarkers</subject><subject>Cell size</subject><subject>Creatine</subject><subject>Creatine Kinase</subject><subject>Creatinine</subject><subject>Exercise</subject><subject>Female</subject><subject>Football</subject><subject>Hematology</subject><subject>Hemoglobin</subject><subject>Humans</subject><subject>L-Lactate Dehydrogenase</subject><subject>Lactate dehydrogenase</subject><subject>Lactic acid</subject><subject>Leukocytes (eosinophilic)</subject><subject>Male</subject><subject>Marathons</subject><subject>Medical laboratories</subject><subject>Physical fitness</subject><subject>Physiology</subject><subject>Population</subject><subject>Potassium</subject><subject>Reference Values</subject><subject>Rugby</subject><subject>Running</subject><subject>Sports medicine</subject><subject>Transaminase</subject><subject>Urea</subject><subject>Variation</subject><subject>Young Adult</subject><issn>1660-4601</issn><issn>1661-7827</issn><issn>1660-4601</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkUtP3DAUha2qqDy3XVaRuulm4N7YcexNJRgNLyHBAthajuMwHjnx1M4g9d_jYWAErGwdfz73Hh1CfiIcUyrhxC1sXM5RQkWhkt_IHnIOE8YBv3-475L9lBYAVDAuf5BdWpU11BXskesznbQvHrVf2VSErjhzwcxt70xW9dAWl7bXY_Dh6VW501H3drQxFW4oZt6Ntjgd5z5L6ZDsdNone_R2HpCH89n99HJyc3txNT29mRiGYpwIlA2UmgkpatlpWlcdw6Y2EgErbKE2TVuCAY7IGoMlctECFw1nKAWTFT0gfze-y1XT29bYYYzaq2V0vY7_VdBOfX4Z3Fw9hWcl8oiyxmzw580ghn859qh6l4z1Xg82rJIqORUZk3Q96_cXdBFWccjx1lTNBTIpM3W8oUwMKUXbbZdBUOua1Oea8odfHyNs8fde6AvZho1W</recordid><startdate>20220305</startdate><enddate>20220305</enddate><creator>Díaz Martínez, Angel Enrique</creator><creator>Alcaide Martín, María José</creator><creator>González-Gross, Marcela</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6215-0093</orcidid><orcidid>https://orcid.org/0000-0001-7757-3235</orcidid><orcidid>https://orcid.org/0000-0003-3472-8107</orcidid></search><sort><creationdate>20220305</creationdate><title>Basal Values of Biochemical and Hematological Parameters in Elite Athletes</title><author>Díaz Martínez, Angel Enrique ; Alcaide Martín, María José ; González-Gross, Marcela</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c418t-819b02a489879fa375f41b7c910151d07cbd20c06114bc12168d068b641984953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Alanine</topic><topic>Alanine Transaminase</topic><topic>Albumins</topic><topic>Aspartate Aminotransferases</topic><topic>Aspartate transaminase</topic><topic>Athletes</topic><topic>Bicycling</topic><topic>Bilirubin</topic><topic>Biochemistry</topic><topic>Biomarkers</topic><topic>Cell size</topic><topic>Creatine</topic><topic>Creatine Kinase</topic><topic>Creatinine</topic><topic>Exercise</topic><topic>Female</topic><topic>Football</topic><topic>Hematology</topic><topic>Hemoglobin</topic><topic>Humans</topic><topic>L-Lactate Dehydrogenase</topic><topic>Lactate dehydrogenase</topic><topic>Lactic acid</topic><topic>Leukocytes (eosinophilic)</topic><topic>Male</topic><topic>Marathons</topic><topic>Medical laboratories</topic><topic>Physical fitness</topic><topic>Physiology</topic><topic>Population</topic><topic>Potassium</topic><topic>Reference Values</topic><topic>Rugby</topic><topic>Running</topic><topic>Sports medicine</topic><topic>Transaminase</topic><topic>Urea</topic><topic>Variation</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Díaz Martínez, Angel Enrique</creatorcontrib><creatorcontrib>Alcaide Martín, María José</creatorcontrib><creatorcontrib>González-Gross, Marcela</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of environmental research and public health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Díaz Martínez, Angel Enrique</au><au>Alcaide Martín, María José</au><au>González-Gross, Marcela</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Basal Values of Biochemical and Hematological Parameters in Elite Athletes</atitle><jtitle>International journal of environmental research and public health</jtitle><addtitle>Int J Environ Res Public Health</addtitle><date>2022-03-05</date><risdate>2022</risdate><volume>19</volume><issue>5</issue><spage>3059</spage><pages>3059-</pages><issn>1660-4601</issn><issn>1661-7827</issn><eissn>1660-4601</eissn><abstract>The purpose of this study was to show how continuous exercise affects the basal values of biochemical and hematological parameters in elite athletes. A total of 14,010 samples (male = 8452 and female = 5558 (March 2011-March 2020)) from 3588 elite athletes (male = 2258 and female = 1330, mean age 24.9 ± 6.9 vs. 24.1 ± 5.5 years, respectively) from 32 sport modalities, were studied over 9 years to check the variation of basal biochemical and hematological parameter values. There were differences seen in the basal values of creatine kinase (CK), urea, creatinine, aspartate transaminase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), potassium, total bilirubin, and eosinophil percentage compared to reference population data. However, other analytes showed narrow ranges of variation like glucose, total protein, albumin, sodium, hemoglobin, mean cell volume (MCV), and platelet count. Exercise produces changes in biochemical and hematological basal values of athletes compared to the general population, with the greatest variation in CK, but AST, ALT, LDH, potassium, and total bilirubin (TBil) show high values in serum, only with a wider distribution of values. The data here reflects the effect of exercise on biochemical and hematological parameter baseline ranges in elite athletes. As clinical laboratories use reference intervals to validate clinical reports, these "pseudo" reference intervals should be used when validating laboratory reports.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>35270750</pmid><doi>10.3390/ijerph19053059</doi><orcidid>https://orcid.org/0000-0002-6215-0093</orcidid><orcidid>https://orcid.org/0000-0001-7757-3235</orcidid><orcidid>https://orcid.org/0000-0003-3472-8107</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1660-4601 |
| ispartof | International journal of environmental research and public health, 2022-03, Vol.19 (5), p.3059 |
| issn | 1660-4601 1661-7827 1660-4601 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8910271 |
| source | MDPI - Multidisciplinary Digital Publishing Institute; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; PubMed Central Open Access |
| subjects | Adolescent Adult Alanine Alanine Transaminase Albumins Aspartate Aminotransferases Aspartate transaminase Athletes Bicycling Bilirubin Biochemistry Biomarkers Cell size Creatine Creatine Kinase Creatinine Exercise Female Football Hematology Hemoglobin Humans L-Lactate Dehydrogenase Lactate dehydrogenase Lactic acid Leukocytes (eosinophilic) Male Marathons Medical laboratories Physical fitness Physiology Population Potassium Reference Values Rugby Running Sports medicine Transaminase Urea Variation Young Adult |
| title | Basal Values of Biochemical and Hematological Parameters in Elite Athletes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T04%3A37%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Basal%20Values%20of%20Biochemical%20and%20Hematological%20Parameters%20in%20Elite%20Athletes&rft.jtitle=International%20journal%20of%20environmental%20research%20and%20public%20health&rft.au=D%C3%ADaz%20Mart%C3%ADnez,%20Angel%20Enrique&rft.date=2022-03-05&rft.volume=19&rft.issue=5&rft.spage=3059&rft.pages=3059-&rft.issn=1660-4601&rft.eissn=1660-4601&rft_id=info:doi/10.3390/ijerph19053059&rft_dat=%3Cproquest_pubme%3E2638713935%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2637681499&rft_id=info:pmid/35270750&rfr_iscdi=true |