The B-Cell-Specific Ablation of B4GALT1 Reduces Cancer Formation and Reverses the Changes in Serum IgG Glycans during the Induction of Mouse Hepatocellular Carcinoma

Serum immunoglobulin G (IgG) glycosylation, especially galactosylation, has been found to be related to a variety of tumors, including hepatocellular carcinoma (HCC). However, whether IgG glycan changes occur in the early stages of HCC formation remains unclear. We found that the galactosylation lev...

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Veröffentlicht in:	Cancers 2022-03, Vol.14 (5), p.1333
Hauptverfasser:	Sha, Jichen, Zhang, Rongrong, Fan, Jiteng, Gu, Yong, Pan, Yiqing, Han, Jing, Xu, Xiaoyan, Ren, Shifang, Gu, Jianxin
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Biomarkers Gender differences Glycosylation Hepatocellular carcinoma Immunoglobulin G Liver cancer Lymphocytes B Polysaccharides Rodents Sex differences Tumor markers Tumors
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