Multilocus Inherited Neoplasia Allele Syndrome (MINAS): an update

Multi-locus Inherited Neoplasia Allele Syndrome (MINAS) refers to individuals with germline pathogenic variants in two or more cancer susceptibility genes(CSGs). With increased use of exome/genome sequencing it would be predicted that detection of MINAS would become more frequent. Here we review rec...

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Veröffentlicht in:	European journal of human genetics : EJHG 2022-03, Vol.30 (3), p.265-270
Hauptverfasser:	McGuigan, Anthony, Whitworth, James, Andreou, Avgi, Hearn, Timothy, Tischkowitz, Marc, Maher, Eamonn R
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles BRCA1 protein BRCA2 protein Exome Exome Sequencing Genetic Predisposition to Disease Genomes Germ-Line Mutation Humans Multiple primary tumors Neoplasms, Multiple Primary - genetics Phenotypes Rare diseases Review Tumors
Online-Zugang:	Volltext
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