Seropositivity of Anti-SARS CoV2 IgG antibodies in health care workers of an Indian tertiary care hospital during COVID-19
Health care workers [HCW] are at a higher risk of infection SARS CoV2 infection due to frequent and close contact to patients with COVID-19. Serum samples from 500 HCW's were tested for SARS CoV2 IgG antibodies in October 2020. A questionnaire was used to collect demographic and clinical data....
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| Veröffentlicht in: | Indian journal of medical microbiology 2022-04, Vol.40 (2), p.228-230 |
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| container_title | Indian journal of medical microbiology |
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| creator | Verma, Anuragani Shukla, Suruchi Verma, Anil K. Puri, Bipin Jain, Amita |
| description | Health care workers [HCW] are at a higher risk of infection SARS CoV2 infection due to frequent and close contact to patients with COVID-19.
Serum samples from 500 HCW's were tested for SARS CoV2 IgG antibodies in October 2020. A questionnaire was used to collect demographic and clinical data. All these HCWs were tested for COVID-19, in 2nd week of September 2020, as a hospital policy.
Anti SARS CoV2 antibodies were detected in 128/ 500 [25.6%] HCWs. A total of 195/ 500 [39%] enrolled cases had already tested positive for Covid-19 at least once in last six months by RT-PCR. Sixty eight percent of HCWs with previous COVID-19 positivity by RT- PCR tested positive for Anti SARS CoV2 antibodies, whereas only 2.76% of asymptomatic HCWs tested positive. Of 121 anti SARS-CoV-2 IgG positive persons, 70 [57.85%] had CT value |
| doi_str_mv | 10.1016/j.ijmmb.2022.02.004 |
| format | Article |
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Serum samples from 500 HCW's were tested for SARS CoV2 IgG antibodies in October 2020. A questionnaire was used to collect demographic and clinical data. All these HCWs were tested for COVID-19, in 2nd week of September 2020, as a hospital policy.
Anti SARS CoV2 antibodies were detected in 128/ 500 [25.6%] HCWs. A total of 195/ 500 [39%] enrolled cases had already tested positive for Covid-19 at least once in last six months by RT-PCR. Sixty eight percent of HCWs with previous COVID-19 positivity by RT- PCR tested positive for Anti SARS CoV2 antibodies, whereas only 2.76% of asymptomatic HCWs tested positive. Of 121 anti SARS-CoV-2 IgG positive persons, 70 [57.85%] had CT value < 25. Low CT value and asymptomatic cases had a strong reverse statistically significant association with SARS CoV2 IgG antibody positivity.
We report that sero-conversion rate in HCWs is similar to that in general population suggesting that preventive practices used in hospitals are satisfactory. Cases with low viral counts in respiratory sample and asymptomatic cases have lower rate of seroconversion.</description><identifier>ISSN: 0255-0857</identifier><identifier>EISSN: 1998-3646</identifier><identifier>DOI: 10.1016/j.ijmmb.2022.02.004</identifier><identifier>PMID: 35277299</identifier><language>eng</language><publisher>United States: Elsevier B.V</publisher><subject>Anti-COVID IgG ; Antibodies, Viral ; COVID-19 ; CT value ; Health Personnel ; Humans ; Immunoglobulin G ; Original ; SARS CoV2 ; SARS-CoV-2 ; Sero-surveillance ; Seroepidemiologic Studies ; Tertiary Care Centers</subject><ispartof>Indian journal of medical microbiology, 2022-04, Vol.40 (2), p.228-230</ispartof><rights>2022 Indian Association of Medical Microbiologists</rights><rights>Copyright © 2022 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved.</rights><rights>2022 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved. 2022 Indian Association of Medical Microbiologists</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c409t-4e5199f5f8bfb9640bb6578e61c6f042e28f25e05636bc66ae27335c5c8e3d5a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,777,781,882,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35277299$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Verma, Anuragani</creatorcontrib><creatorcontrib>Shukla, Suruchi</creatorcontrib><creatorcontrib>Verma, Anil K.</creatorcontrib><creatorcontrib>Puri, Bipin</creatorcontrib><creatorcontrib>Jain, Amita</creatorcontrib><title>Seropositivity of Anti-SARS CoV2 IgG antibodies in health care workers of an Indian tertiary care hospital during COVID-19</title><title>Indian journal of medical microbiology</title><addtitle>Indian J Med Microbiol</addtitle><description>Health care workers [HCW] are at a higher risk of infection SARS CoV2 infection due to frequent and close contact to patients with COVID-19.
Serum samples from 500 HCW's were tested for SARS CoV2 IgG antibodies in October 2020. A questionnaire was used to collect demographic and clinical data. All these HCWs were tested for COVID-19, in 2nd week of September 2020, as a hospital policy.
Anti SARS CoV2 antibodies were detected in 128/ 500 [25.6%] HCWs. A total of 195/ 500 [39%] enrolled cases had already tested positive for Covid-19 at least once in last six months by RT-PCR. Sixty eight percent of HCWs with previous COVID-19 positivity by RT- PCR tested positive for Anti SARS CoV2 antibodies, whereas only 2.76% of asymptomatic HCWs tested positive. Of 121 anti SARS-CoV-2 IgG positive persons, 70 [57.85%] had CT value < 25. Low CT value and asymptomatic cases had a strong reverse statistically significant association with SARS CoV2 IgG antibody positivity.
We report that sero-conversion rate in HCWs is similar to that in general population suggesting that preventive practices used in hospitals are satisfactory. Cases with low viral counts in respiratory sample and asymptomatic cases have lower rate of seroconversion.</description><subject>Anti-COVID IgG</subject><subject>Antibodies, Viral</subject><subject>COVID-19</subject><subject>CT value</subject><subject>Health Personnel</subject><subject>Humans</subject><subject>Immunoglobulin G</subject><subject>Original</subject><subject>SARS CoV2</subject><subject>SARS-CoV-2</subject><subject>Sero-surveillance</subject><subject>Seroepidemiologic Studies</subject><subject>Tertiary Care Centers</subject><issn>0255-0857</issn><issn>1998-3646</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UdtqGzEQFaWhcdN-QaHoB9bV6rarhxaM06aGQCBu8yq02ll7XHtlJMUl_frKcRval8DAoJlzzszoEPKuZtOa1frDZoqb3a6bcsb5lJVg8gWZ1Ma0ldBSvyQTxpWqWKuac_I6pQ0rb2nkK3IuFG8absyE_FpCDPuQMOMB8wMNA52NGavl7HZJ5-GO08XqirpS6kKPkCiOdA1um9fUuwj0Z4g_IKYjz410MfZYUoaY0cWHE2Qd0h6z29L-PuK4ovObu8VlVZs35Gxw2wRv_-QL8v3L52_zr9X1zdViPruuvGQmVxJUuWlQQ9sNndGSdZ1WTQu69npgkgNvB66AKS1057V2wBshlFe-BdErJy7Ip5Pu_r7bQe9hzNFt7T7iruxog0P7f2fEtV2Fg20NEy3jRUCcBHwMKUUYnrg1s0cr7MY-WmGPVlhWgsnCev_v2CfO378vgI8nAJTjDwjRJo8weugxgs-2D_jsgN8Wn5zG</recordid><startdate>20220401</startdate><enddate>20220401</enddate><creator>Verma, Anuragani</creator><creator>Shukla, Suruchi</creator><creator>Verma, Anil K.</creator><creator>Puri, Bipin</creator><creator>Jain, Amita</creator><general>Elsevier B.V</general><general>Indian Association of Medical Microbiologists. Published by Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20220401</creationdate><title>Seropositivity of Anti-SARS CoV2 IgG antibodies in health care workers of an Indian tertiary care hospital during COVID-19</title><author>Verma, Anuragani ; Shukla, Suruchi ; Verma, Anil K. ; Puri, Bipin ; Jain, Amita</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c409t-4e5199f5f8bfb9640bb6578e61c6f042e28f25e05636bc66ae27335c5c8e3d5a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Anti-COVID IgG</topic><topic>Antibodies, Viral</topic><topic>COVID-19</topic><topic>CT value</topic><topic>Health Personnel</topic><topic>Humans</topic><topic>Immunoglobulin G</topic><topic>Original</topic><topic>SARS CoV2</topic><topic>SARS-CoV-2</topic><topic>Sero-surveillance</topic><topic>Seroepidemiologic Studies</topic><topic>Tertiary Care Centers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Verma, Anuragani</creatorcontrib><creatorcontrib>Shukla, Suruchi</creatorcontrib><creatorcontrib>Verma, Anil K.</creatorcontrib><creatorcontrib>Puri, Bipin</creatorcontrib><creatorcontrib>Jain, Amita</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Indian journal of medical microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Verma, Anuragani</au><au>Shukla, Suruchi</au><au>Verma, Anil K.</au><au>Puri, Bipin</au><au>Jain, Amita</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Seropositivity of Anti-SARS CoV2 IgG antibodies in health care workers of an Indian tertiary care hospital during COVID-19</atitle><jtitle>Indian journal of medical microbiology</jtitle><addtitle>Indian J Med Microbiol</addtitle><date>2022-04-01</date><risdate>2022</risdate><volume>40</volume><issue>2</issue><spage>228</spage><epage>230</epage><pages>228-230</pages><issn>0255-0857</issn><eissn>1998-3646</eissn><abstract>Health care workers [HCW] are at a higher risk of infection SARS CoV2 infection due to frequent and close contact to patients with COVID-19.
Serum samples from 500 HCW's were tested for SARS CoV2 IgG antibodies in October 2020. A questionnaire was used to collect demographic and clinical data. All these HCWs were tested for COVID-19, in 2nd week of September 2020, as a hospital policy.
Anti SARS CoV2 antibodies were detected in 128/ 500 [25.6%] HCWs. A total of 195/ 500 [39%] enrolled cases had already tested positive for Covid-19 at least once in last six months by RT-PCR. Sixty eight percent of HCWs with previous COVID-19 positivity by RT- PCR tested positive for Anti SARS CoV2 antibodies, whereas only 2.76% of asymptomatic HCWs tested positive. Of 121 anti SARS-CoV-2 IgG positive persons, 70 [57.85%] had CT value < 25. Low CT value and asymptomatic cases had a strong reverse statistically significant association with SARS CoV2 IgG antibody positivity.
We report that sero-conversion rate in HCWs is similar to that in general population suggesting that preventive practices used in hospitals are satisfactory. Cases with low viral counts in respiratory sample and asymptomatic cases have lower rate of seroconversion.</abstract><cop>United States</cop><pub>Elsevier B.V</pub><pmid>35277299</pmid><doi>10.1016/j.ijmmb.2022.02.004</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Indian journal of medical microbiology, 2022-04, Vol.40 (2), p.228-230 |
| issn | 0255-0857 1998-3646 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Anti-COVID IgG Antibodies, Viral COVID-19 CT value Health Personnel Humans Immunoglobulin G Original SARS CoV2 SARS-CoV-2 Sero-surveillance Seroepidemiologic Studies Tertiary Care Centers |
| title | Seropositivity of Anti-SARS CoV2 IgG antibodies in health care workers of an Indian tertiary care hospital during COVID-19 |
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