Long noncoding RNA CCAT2 reduces chemosensitivity to 5‐fluorouracil in breast cancer cells by activating the mTOR axis

Breast cancer (BC) is the most prevalent cancer in women and the second leading cause for cancer‐related death in women. LncRNA CCAT2 is involved in BC cell drug sensitivity. Drug resistance of BC cells after chemotherapy is the main obstacle to therapeutic effects. This study explored whether BC ce...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular and molecular medicine 2022-03, Vol.26 (5), p.1392-1401
Hauptverfasser:	Zhou, Daoping, Gu, Juan, Wang, Yueping, Luo, Bing, Feng, Mei, Wang, Xuedong
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Fluorouracil 5‐Fu Apoptosis Apoptosis - genetics Biopsy Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer therapies CCAT2 Cell cycle Cell Line, Tumor Cell proliferation Cell Proliferation - genetics Chemotherapy Correlation analysis Drug resistance Epithelial cells Female Flow cytometry Fluorouracil - pharmacology Fluorouracil - therapeutic use Gene Expression Regulation, Neoplastic Growth rate Health care Humans mRNA mTOR pathway Non-coding RNA Original Plasmids Remission (Medicine) RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism S phase TOR protein TOR Serine-Threonine Kinases - genetics TOR Serine-Threonine Kinases - metabolism Tumors Xenografts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!