Cardiotoxicity from Capecitabine Chemotherapy: Prospective Study of Incidence at Rest and During Physical Exercise

Physical activity may increase the risk of cardiotoxicity (myocardial ischemia, major arrhythmias) of 5-Fluorouracil, but this risk has never been investigated for its prodrug capecitabine. One hundred and ninety-two consecutive patients undergoing capecitabine chemotherapy from December 1, 2010 thr...

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Veröffentlicht in:	The oncologist (Dayton, Ohio) Ohio), 2022-03, Vol.27 (2), p.e158-e167
Hauptverfasser:	Lestuzzi, Chiara, Stolfo, Davide, De Paoli, Antonino, Banzato, Alberto, Buonadonna, Angela, Bidoli, Ettore, Tartuferi, Lucia, Viel, Elda, De Angelis, Giulia, Lonardi, Sara, Innocente, Roberto, Berretta, Massimiliano, Bergamo, Francesca, Guglielmi, Alessandra, Sinagra, Gianfranco, Herrmann, Joerg
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimitotic agents Antineoplastic agents Arrhythmias, Cardiac - epidemiology Cancer Capecitabine Capecitabine - toxicity Cardiotoxicity - etiology Chemotherapy Complications and side effects Development and progression Diagnosis Dosage and administration Electrocardiogram Electrocardiography Exercise Exercise tests Health aspects Heart Heart diseases Humans Incidence Ischemia New Drug Development and Clinical Pharmacology Pharmaceutical industry Physical fitness Prospective Studies Risk factors Stress (Psychology) Tachycardia
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