Single-molecule imaging of IQGAP1 regulating actin filament dynamics

IQGAP is a conserved family of actin-binding proteins with essential roles in cell motility, cytokinesis, and cell adhesion, yet there remains a limited understanding of how IQGAP proteins directly influence actin filament dynamics. To close this gap, we used single-molecule and single-filament tota...

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Veröffentlicht in:Molecular biology of the cell 2022-01, Vol.33 (1), p.ar2-ar2
Hauptverfasser: Hoeprich, Gregory J, Sinclair, Amy N, Shekhar, Shashank, Goode, Bruce L
Format: Artikel
Sprache:eng
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