Collagen I Fibrous Substrates Modulate the Proliferation and Secretome of Estrogen Receptor-Positive Breast Tumor Cells in a Hormone-Restricted Microenvironment

The fibril orientation of type I collagen has been shown to contribute to tumor invasion and metabolic changes. Yet, there is limited information about its impact on tumor cells’ behavior in a restrictive growth environment. Restrictive growth environments are generated by the inhibition of a prolif...

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Veröffentlicht in:ACS biomaterials science & engineering 2021-06, Vol.7 (6), p.2430-2443
Hauptverfasser: Reyes-Ramos, Ana M, Álvarez-García, Yasmín R, Solodin, Natalia, Almodovar, Jorge, Alarid, Elaine T, Torres-Garcia, Wandaliz, Domenech, Maribella
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Sprache:eng
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