The impact of obesity and bariatric surgery on the immune microenvironment of the endometrium

Background The incidence of endometrial cancer is rising in parallel with the obesity epidemic. Obesity increases endometrial cancer risk and weight loss is protective, but the underlying mechanisms are incompletely understood. We hypothesise that the immune microenvironment may influence susceptibi...

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Veröffentlicht in:	International Journal of Obesity 2022-03, Vol.46 (3), p.605-612
Hauptverfasser:	Naqvi, Anie, MacKintosh, Michelle L., Derbyshire, Abigail E., Tsakiroglou, Anna-Maria, Walker, Thomas D. J., McVey, Rhona J., Bolton, James, Fergie, Martin, Bagley, Steven, Ashton, Garry, Pemberton, Philip W., Syed, Akheel A., Ammori, Basil J., Byers, Richard, Crosbie, Emma J.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250 631/67 82 82/51 Bariatric Surgery Biomarkers Body mass index Body size Body weight loss Cancer CD3 antigen CD56 antigen CD8 antigen Cell density Diet Endometrial cancer Endometrial Neoplasms - epidemiology Endometrium Endometrium - pathology Epidemiology Female Foxp3 protein Gastrointestinal surgery Health Promotion and Disease Prevention Health risks Humans Hypocaloric diet Immune system Immunofluorescence Immunology Immunosurveillance Inflammation Interleukin 6 Interleukin-6 - metabolism Internal Medicine Male Medicine Medicine & Public Health Metabolic Diseases Microenvironments Nutrient deficiency Obesity Obesity - complications Obesity - surgery Paraffin Paraffins PD-1 protein Prospective Studies Public Health Surgery Tumor Microenvironment Tumor necrosis factor-α Weight control Weight Loss Weight loss measurement
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