Kinesin-14 motors participate in a force balance at microtubule plus-ends to regulate dynamic instability

Kinesin-14 molecular motors represent an essential class of proteins that bind microtubules and walk toward their minus-ends. Previous studies have described important roles for Kinesin-14 motors at microtubule minus-ends, but their role in regulating plus-end dynamics remains controversial. Kinesin...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2022-02, Vol.119 (8), p.1-12
Hauptverfasser:	Ogren, Allison, Parmar, Sneha, Mukherjee, Soumya, Gonzalez, Samuel J., Plooster, Melissa, McClellan, Mark, Mannava, Anirudh G., Davidson, Elliott, Davis, Trisha N., Gardner, Melissa K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences Chromosome Segregation Dynamic stability Kinesin Kinesins - metabolism Kinesins - physiology Microtubule Proteins - metabolism Microtubule-Associated Proteins - metabolism Microtubules Microtubules - metabolism Microtubules - physiology Molecular motors Protein Binding Proteins Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - metabolism Spindle Apparatus - metabolism Tethering
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