PCP Protein Inversin Regulates Testis Function Through Changes in Cytoskeletal Organization of Actin and Microtubules

Inversin is an integrated component of the Frizzled (Fzd)/Dishevelled (Dvl)/Diversin planar cell polarity (PCP) complex that is known to work in concert with the Van Gogh-like protein (eg, Vangl2)/Prickle PCP complex to support tissue and organ development including the brain, kidney, pancreas, and...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2022-04, Vol.163 (4), p.1
Hauptverfasser:	Li, Linxi, Gao, Sheng, Wang, Lingling, Bu, Tiao, Chu, Jinjin, Lv, Lixiu, Tahir, Anam, Mao, Baiping, Li, Huitao, Li, Xiaoheng, Wang, Yiyan, Wu, Xiaolong, Ge, Renshan, Cheng, C Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actins - metabolism Adenoviruses Animals Blood-Testis Barrier - metabolism Cytoskeleton Cytoskeleton - metabolism Defects Dishevelled protein Endocrinology Frizzled protein Gene expression Genetic transcription In vivo methods and tests Kidneys Male Microtubules Microtubules - metabolism Physiological effects Polymerization Proteins Rats Rats, Sprague-Dawley RNA RNA-mediated interference Scientific equipment and supplies industry Sertoli Cells - metabolism siRNA Spermatids Spermatids - metabolism Spermatogenesis Spermatogenesis - physiology Testes Testis - metabolism Transcription Factors - metabolism
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