Novel Redirected T-Cell Immunotherapies for Advanced Prostate Cancer

Immunotherapy has failed to achieve durable remissions in advanced prostate cancer patients. More potent T-cell-redirecting strategies may be needed to overcome the immunologically exclusive and suppressive tumor microenvironment. Clinical trials are underway, seeking to define the optimal target fo...

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Veröffentlicht in:	Clinical cancer research 2022-02, Vol.28 (4), p.576-584
Hauptverfasser:	Dorff, Tanya B, Narayan, Vivek, Forman, Stephen J, Zang, Peter D, Fraietta, Joseph A, June, Carl H, Haas, Naomi B, Priceman, Saul J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Bispecific - therapeutic use Humans Immunotherapy - methods Male Prostatic Neoplasms - pathology T-Lymphocytes Tumor Microenvironment
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