Mycosis fungoides‐derived exosomes promote cell motility and are enriched with microRNA‐155 and microRNA‐1246, and their plasma‐cell‐free expression may serve as a potential biomarker for disease burden

Summary Background Literature regarding exosomes as mediators in intercellular communication to promote progression in mycosis fungoides (MF) is lacking. Objectives To characterize MF‐derived exosomes and their involvement in the disease. Methods Exosomes were isolated by ultracentrifugation from cu...

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Veröffentlicht in:	British journal of dermatology (1951) 2021-11, Vol.185 (5), p.999-1012
Hauptverfasser:	Moyal, L., Arkin, C., Gorovitz‐Haris, B., Querfeld, C., Rosen, S., Knaneh, J., Amitay‐Laish, I., Prag‐Naveh, H., Jacob‐Hirsch, J., Hodak, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biomarkers, Tumor - genetics CD81 antigen Cell migration Cell Movement Electron microscopy Exosomes Exosomes - genetics Fungal infections Humans Labeling Lymphoma MicroRNAs MicroRNAs - genetics miRNA Motility Mycosis Mycosis fungoides Mycosis Fungoides - genetics Plasma Plasma levels Polymerase chain reaction Skin Neoplasms - genetics Tumor cell lines Tumors Ultracentrifugation
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