T-replete HLA-matched grafts vs T-depleted HLA-mismatched grafts in inborn errors of immunity

Hematopoietic cell transplantation (HCT) has become standard-of-care for an increasing number of inborn errors of immunity (IEI). This report is the first to compare transplant outcomes according to T-cell–replete (ie, T-replete) HLA-matched grafts using alemtuzumab (n = 117) and T-cell–depleted (ie...

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Veröffentlicht in:	Blood advances 2022-02, Vol.6 (4), p.1319-1328
Hauptverfasser:	Lum, Su Han, Greener, Sinéad, Perez-Heras, Inigo, Drozdov, Daniel, Payne, Rebecca P., Watson, Helen, Carruthers, Kay, January, Robert, Nademi, Zohreh, Owens, Stephen, Williams, Eleri, Waugh, Sheila, Burton-Fanning, Shirelle, Leahy, Timmothy Ronan, Cant, Andrew, Abinun, Mario, Flood, Terry, Hambleton, Sophie, Gennery, Andrew R., Slatter, Mary
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD19 Child Graft vs Host Disease - etiology Hematopoietic Stem Cell Transplantation - adverse effects Humans Receptors, Antigen, T-Cell, alpha-beta Transplantation Transplantation, Homologous - adverse effects Unrelated Donors
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