SARS-CoV-2 spike antigen quantification by targeted mass spectrometry of a virus-based vaccine

•The spike glycoprotein of SARS-CoV-2 mediates virus binding to host cells’ receptors and is a key target for vaccines development.•The spike induces a specific immune response. Yet, no method was developed for spike quantification.•A mass spectrometric based method for spike quantification was deve...

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Veröffentlicht in:	Journal of virological methods 2022-05, Vol.303, p.114498-114498, Article 114498
Hauptverfasser:	Rosen, Osnat, Jayson, Avital, Dor, Eyal, Epstein, Eyal, Makovitzki, Arik, Cherry, Lilach, Lupu, Edith, Monash, Arik, Borni, Sarah, Baruchi, Tzadok, Laskar, Orly, Shmaya, Shlomo, Rosenfeld, Ronit, Levy, Yinon, Schuster, Ofir, Feldberg, Liron
Format:	Artikel
Sprache:	eng
Schlagworte:	COVID-19 - prevention & control COVID-19 Vaccines Humans Mass Spectrometry Quantification SARS-CoV-2 Spike Spike Glycoprotein, Coronavirus Vaccine Viral Vaccines
Online-Zugang:	Volltext
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