Non-compliance with colonoscopy after a positive faecal immunochemical test doubles the risk of dying from colorectal cancer

BackgroundThe risk of colorectal cancer (CRC) among subjects with a positive faecal immunochemical test (FIT) who do not undergo a colonoscopy is unknown. We estimated whether non-compliance with colonoscopy after a positive FIT is associated with increased CRC incidence and mortality.MethodsThe FIT...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Gut 2022-03, Vol.71 (3), p.561-567
Hauptverfasser: Zorzi, Manuel, Battagello, Jessica, Selby, Kevin, Capodaglio, Giulia, Baracco, Susanna, Rizzato, Silvia, Chinellato, Enrico, Guzzinati, Stefano, Rugge, Massimo
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 567
container_issue 3
container_start_page 561
container_title Gut
container_volume 71
creator Zorzi, Manuel
Battagello, Jessica
Selby, Kevin
Capodaglio, Giulia
Baracco, Susanna
Rizzato, Silvia
Chinellato, Enrico
Guzzinati, Stefano
Rugge, Massimo
description BackgroundThe risk of colorectal cancer (CRC) among subjects with a positive faecal immunochemical test (FIT) who do not undergo a colonoscopy is unknown. We estimated whether non-compliance with colonoscopy after a positive FIT is associated with increased CRC incidence and mortality.MethodsThe FIT-based CRC screening programme in the Veneto region (Italy) invited persons aged 50 to 69 years with a positive FIT (>20 µg Hb/g faeces) for diagnostic colonoscopy at an endoscopic referral centre. In this retrospective cohort study, we compared the 10-year cumulative CRC incidence and mortality among FIT positives who completed a diagnostic colonoscopy within the programme (compliers) and those who did not (non-compliers), using the Kaplan-Meier estimator and Cox-Aalen models.ResultsSome 88 013 patients who were FIT positive complied with colonoscopy (males: 56.1%; aged 50–59 years: 49.1%) while 23 410 did not (males: 54.6%; aged 50–59 years: 44.9%).The 10-year cumulative incidence of CRC was 44.7 per 1000 (95% CI, 43.1 to 46.3) among colonoscopy compliers and 54.3 per 1000 (95% CI, 49.9 to 58.7) in non-compliers, while the cumulative mortality for CRC was 6.8 per 1000 (95% CI, 5.9 to 7.6) and 16.0 per 1000 (95% CI, 13.1 to 18.9), respectively. The risk of dying of CRC among non-compliers was 103% higher than among compliers (adjusted HR, 2.03; 95% CI, 1.68 to 2.44).ConclusionThe excess risk of CRC death among those not completing colonoscopy after a positive faecal occult blood test should prompt screening programmes to adopt effective interventions to increase compliance in this high-risk population.
doi_str_mv 10.1136/gutjnl-2020-322192
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8862019</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2507727300</sourcerecordid><originalsourceid>FETCH-LOGICAL-b507t-334fa5f7f279f6f1492b0c537ea955ebae7f48c65f55b96bbc653f34bd56ee3f3</originalsourceid><addsrcrecordid>eNqNkUuPFCEUhYnROO3oH3BhSNy4qZFHAcXGxEwcNZnoRtcEaOimrYIWqDGd-OOHtsb2sTCuuDd899xzcwB4itEFxpS_3Mx1F8eOIII6SgiW5B5Y4Z4PrRuG-2CFEBYdE708A49K2SGEhkHih-CMUjFIydkKfP-QYmfTtB-DjtbBb6FuoU1jiqnYtD9A7avLUMN9KqGGGwe9dlaPMEzTHJPduikc2-pKhes0m9EVWLcO5lC-wOTh-hDiBvqcph-y2dnacHtclh-DB16PxT25e8_B56s3ny7fddcf376_fH3dGYZE7SjtvWZeeCKk5x73khhkGRVOS8ac0U74frCcecaM5Ma0knramzXjzrXqHLxadPezmdzaulizHtU-h0nng0o6qD9_YtiqTbpRw8AJwrIJvLgTyOnr3E5VUyjWjaOOLs1FkeZTEEERaujzv9BdmnNs5ynCCed941ijyELZnErJzp_MYKSO4aolXHUMVy3htqFnv59xGvmZZgO6BTDT7v8EL37xJ5v_GLgFC47CVw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2626647275</pqid></control><display><type>article</type><title>Non-compliance with colonoscopy after a positive faecal immunochemical test doubles the risk of dying from colorectal cancer</title><source>MEDLINE</source><source>PubMed Central</source><creator>Zorzi, Manuel ; Battagello, Jessica ; Selby, Kevin ; Capodaglio, Giulia ; Baracco, Susanna ; Rizzato, Silvia ; Chinellato, Enrico ; Guzzinati, Stefano ; Rugge, Massimo</creator><creatorcontrib>Zorzi, Manuel ; Battagello, Jessica ; Selby, Kevin ; Capodaglio, Giulia ; Baracco, Susanna ; Rizzato, Silvia ; Chinellato, Enrico ; Guzzinati, Stefano ; Rugge, Massimo</creatorcontrib><description>BackgroundThe risk of colorectal cancer (CRC) among subjects with a positive faecal immunochemical test (FIT) who do not undergo a colonoscopy is unknown. We estimated whether non-compliance with colonoscopy after a positive FIT is associated with increased CRC incidence and mortality.MethodsThe FIT-based CRC screening programme in the Veneto region (Italy) invited persons aged 50 to 69 years with a positive FIT (&gt;20 µg Hb/g faeces) for diagnostic colonoscopy at an endoscopic referral centre. In this retrospective cohort study, we compared the 10-year cumulative CRC incidence and mortality among FIT positives who completed a diagnostic colonoscopy within the programme (compliers) and those who did not (non-compliers), using the Kaplan-Meier estimator and Cox-Aalen models.ResultsSome 88 013 patients who were FIT positive complied with colonoscopy (males: 56.1%; aged 50–59 years: 49.1%) while 23 410 did not (males: 54.6%; aged 50–59 years: 44.9%).The 10-year cumulative incidence of CRC was 44.7 per 1000 (95% CI, 43.1 to 46.3) among colonoscopy compliers and 54.3 per 1000 (95% CI, 49.9 to 58.7) in non-compliers, while the cumulative mortality for CRC was 6.8 per 1000 (95% CI, 5.9 to 7.6) and 16.0 per 1000 (95% CI, 13.1 to 18.9), respectively. The risk of dying of CRC among non-compliers was 103% higher than among compliers (adjusted HR, 2.03; 95% CI, 1.68 to 2.44).ConclusionThe excess risk of CRC death among those not completing colonoscopy after a positive faecal occult blood test should prompt screening programmes to adopt effective interventions to increase compliance in this high-risk population.</description><identifier>ISSN: 0017-5749</identifier><identifier>ISSN: 1468-3288</identifier><identifier>EISSN: 1468-3288</identifier><identifier>DOI: 10.1136/gutjnl-2020-322192</identifier><identifier>PMID: 33789965</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and British Society of Gastroenterology</publisher><subject>Aged ; cancer prevention ; Colon ; Colonoscopy ; Colorectal cancer ; colorectal cancer screening ; Colorectal carcinoma ; Colorectal Neoplasms - diagnosis ; Colorectal Neoplasms - epidemiology ; Compliance ; Early Detection of Cancer ; Emigration ; Endoscopy ; Feces ; Female ; Humans ; Incidence ; Italy ; Male ; Middle Aged ; Mortality ; Patient Compliance ; Patients ; Retrospective Studies ; Risk Factors ; Software ; Survival Rate ; Tumors</subject><ispartof>Gut, 2022-03, Vol.71 (3), p.561-567</ispartof><rights>Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2022 Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b507t-334fa5f7f279f6f1492b0c537ea955ebae7f48c65f55b96bbc653f34bd56ee3f3</citedby><cites>FETCH-LOGICAL-b507t-334fa5f7f279f6f1492b0c537ea955ebae7f48c65f55b96bbc653f34bd56ee3f3</cites><orcidid>0000-0002-0679-0563 ; 0000-0001-6025-5214</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862019/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862019/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33789965$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zorzi, Manuel</creatorcontrib><creatorcontrib>Battagello, Jessica</creatorcontrib><creatorcontrib>Selby, Kevin</creatorcontrib><creatorcontrib>Capodaglio, Giulia</creatorcontrib><creatorcontrib>Baracco, Susanna</creatorcontrib><creatorcontrib>Rizzato, Silvia</creatorcontrib><creatorcontrib>Chinellato, Enrico</creatorcontrib><creatorcontrib>Guzzinati, Stefano</creatorcontrib><creatorcontrib>Rugge, Massimo</creatorcontrib><title>Non-compliance with colonoscopy after a positive faecal immunochemical test doubles the risk of dying from colorectal cancer</title><title>Gut</title><addtitle>Gut</addtitle><addtitle>Gut</addtitle><description>BackgroundThe risk of colorectal cancer (CRC) among subjects with a positive faecal immunochemical test (FIT) who do not undergo a colonoscopy is unknown. We estimated whether non-compliance with colonoscopy after a positive FIT is associated with increased CRC incidence and mortality.MethodsThe FIT-based CRC screening programme in the Veneto region (Italy) invited persons aged 50 to 69 years with a positive FIT (&gt;20 µg Hb/g faeces) for diagnostic colonoscopy at an endoscopic referral centre. In this retrospective cohort study, we compared the 10-year cumulative CRC incidence and mortality among FIT positives who completed a diagnostic colonoscopy within the programme (compliers) and those who did not (non-compliers), using the Kaplan-Meier estimator and Cox-Aalen models.ResultsSome 88 013 patients who were FIT positive complied with colonoscopy (males: 56.1%; aged 50–59 years: 49.1%) while 23 410 did not (males: 54.6%; aged 50–59 years: 44.9%).The 10-year cumulative incidence of CRC was 44.7 per 1000 (95% CI, 43.1 to 46.3) among colonoscopy compliers and 54.3 per 1000 (95% CI, 49.9 to 58.7) in non-compliers, while the cumulative mortality for CRC was 6.8 per 1000 (95% CI, 5.9 to 7.6) and 16.0 per 1000 (95% CI, 13.1 to 18.9), respectively. The risk of dying of CRC among non-compliers was 103% higher than among compliers (adjusted HR, 2.03; 95% CI, 1.68 to 2.44).ConclusionThe excess risk of CRC death among those not completing colonoscopy after a positive faecal occult blood test should prompt screening programmes to adopt effective interventions to increase compliance in this high-risk population.</description><subject>Aged</subject><subject>cancer prevention</subject><subject>Colon</subject><subject>Colonoscopy</subject><subject>Colorectal cancer</subject><subject>colorectal cancer screening</subject><subject>Colorectal carcinoma</subject><subject>Colorectal Neoplasms - diagnosis</subject><subject>Colorectal Neoplasms - epidemiology</subject><subject>Compliance</subject><subject>Early Detection of Cancer</subject><subject>Emigration</subject><subject>Endoscopy</subject><subject>Feces</subject><subject>Female</subject><subject>Humans</subject><subject>Incidence</subject><subject>Italy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Patient Compliance</subject><subject>Patients</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Software</subject><subject>Survival Rate</subject><subject>Tumors</subject><issn>0017-5749</issn><issn>1468-3288</issn><issn>1468-3288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>ACMMV</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkUuPFCEUhYnROO3oH3BhSNy4qZFHAcXGxEwcNZnoRtcEaOimrYIWqDGd-OOHtsb2sTCuuDd899xzcwB4itEFxpS_3Mx1F8eOIII6SgiW5B5Y4Z4PrRuG-2CFEBYdE708A49K2SGEhkHih-CMUjFIydkKfP-QYmfTtB-DjtbBb6FuoU1jiqnYtD9A7avLUMN9KqGGGwe9dlaPMEzTHJPduikc2-pKhes0m9EVWLcO5lC-wOTh-hDiBvqcph-y2dnacHtclh-DB16PxT25e8_B56s3ny7fddcf376_fH3dGYZE7SjtvWZeeCKk5x73khhkGRVOS8ac0U74frCcecaM5Ma0knramzXjzrXqHLxadPezmdzaulizHtU-h0nng0o6qD9_YtiqTbpRw8AJwrIJvLgTyOnr3E5VUyjWjaOOLs1FkeZTEEERaujzv9BdmnNs5ynCCed941ijyELZnErJzp_MYKSO4aolXHUMVy3htqFnv59xGvmZZgO6BTDT7v8EL37xJ5v_GLgFC47CVw</recordid><startdate>20220301</startdate><enddate>20220301</enddate><creator>Zorzi, Manuel</creator><creator>Battagello, Jessica</creator><creator>Selby, Kevin</creator><creator>Capodaglio, Giulia</creator><creator>Baracco, Susanna</creator><creator>Rizzato, Silvia</creator><creator>Chinellato, Enrico</creator><creator>Guzzinati, Stefano</creator><creator>Rugge, Massimo</creator><general>BMJ Publishing Group Ltd and British Society of Gastroenterology</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-0679-0563</orcidid><orcidid>https://orcid.org/0000-0001-6025-5214</orcidid></search><sort><creationdate>20220301</creationdate><title>Non-compliance with colonoscopy after a positive faecal immunochemical test doubles the risk of dying from colorectal cancer</title><author>Zorzi, Manuel ; Battagello, Jessica ; Selby, Kevin ; Capodaglio, Giulia ; Baracco, Susanna ; Rizzato, Silvia ; Chinellato, Enrico ; Guzzinati, Stefano ; Rugge, Massimo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b507t-334fa5f7f279f6f1492b0c537ea955ebae7f48c65f55b96bbc653f34bd56ee3f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Aged</topic><topic>cancer prevention</topic><topic>Colon</topic><topic>Colonoscopy</topic><topic>Colorectal cancer</topic><topic>colorectal cancer screening</topic><topic>Colorectal carcinoma</topic><topic>Colorectal Neoplasms - diagnosis</topic><topic>Colorectal Neoplasms - epidemiology</topic><topic>Compliance</topic><topic>Early Detection of Cancer</topic><topic>Emigration</topic><topic>Endoscopy</topic><topic>Feces</topic><topic>Female</topic><topic>Humans</topic><topic>Incidence</topic><topic>Italy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Patient Compliance</topic><topic>Patients</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Software</topic><topic>Survival Rate</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zorzi, Manuel</creatorcontrib><creatorcontrib>Battagello, Jessica</creatorcontrib><creatorcontrib>Selby, Kevin</creatorcontrib><creatorcontrib>Capodaglio, Giulia</creatorcontrib><creatorcontrib>Baracco, Susanna</creatorcontrib><creatorcontrib>Rizzato, Silvia</creatorcontrib><creatorcontrib>Chinellato, Enrico</creatorcontrib><creatorcontrib>Guzzinati, Stefano</creatorcontrib><creatorcontrib>Rugge, Massimo</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Gut</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zorzi, Manuel</au><au>Battagello, Jessica</au><au>Selby, Kevin</au><au>Capodaglio, Giulia</au><au>Baracco, Susanna</au><au>Rizzato, Silvia</au><au>Chinellato, Enrico</au><au>Guzzinati, Stefano</au><au>Rugge, Massimo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Non-compliance with colonoscopy after a positive faecal immunochemical test doubles the risk of dying from colorectal cancer</atitle><jtitle>Gut</jtitle><stitle>Gut</stitle><addtitle>Gut</addtitle><date>2022-03-01</date><risdate>2022</risdate><volume>71</volume><issue>3</issue><spage>561</spage><epage>567</epage><pages>561-567</pages><issn>0017-5749</issn><issn>1468-3288</issn><eissn>1468-3288</eissn><abstract>BackgroundThe risk of colorectal cancer (CRC) among subjects with a positive faecal immunochemical test (FIT) who do not undergo a colonoscopy is unknown. We estimated whether non-compliance with colonoscopy after a positive FIT is associated with increased CRC incidence and mortality.MethodsThe FIT-based CRC screening programme in the Veneto region (Italy) invited persons aged 50 to 69 years with a positive FIT (&gt;20 µg Hb/g faeces) for diagnostic colonoscopy at an endoscopic referral centre. In this retrospective cohort study, we compared the 10-year cumulative CRC incidence and mortality among FIT positives who completed a diagnostic colonoscopy within the programme (compliers) and those who did not (non-compliers), using the Kaplan-Meier estimator and Cox-Aalen models.ResultsSome 88 013 patients who were FIT positive complied with colonoscopy (males: 56.1%; aged 50–59 years: 49.1%) while 23 410 did not (males: 54.6%; aged 50–59 years: 44.9%).The 10-year cumulative incidence of CRC was 44.7 per 1000 (95% CI, 43.1 to 46.3) among colonoscopy compliers and 54.3 per 1000 (95% CI, 49.9 to 58.7) in non-compliers, while the cumulative mortality for CRC was 6.8 per 1000 (95% CI, 5.9 to 7.6) and 16.0 per 1000 (95% CI, 13.1 to 18.9), respectively. The risk of dying of CRC among non-compliers was 103% higher than among compliers (adjusted HR, 2.03; 95% CI, 1.68 to 2.44).ConclusionThe excess risk of CRC death among those not completing colonoscopy after a positive faecal occult blood test should prompt screening programmes to adopt effective interventions to increase compliance in this high-risk population.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and British Society of Gastroenterology</pub><pmid>33789965</pmid><doi>10.1136/gutjnl-2020-322192</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-0679-0563</orcidid><orcidid>https://orcid.org/0000-0001-6025-5214</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0017-5749
ispartof Gut, 2022-03, Vol.71 (3), p.561-567
issn 0017-5749
1468-3288
1468-3288
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8862019
source MEDLINE; PubMed Central
subjects Aged
cancer prevention
Colon
Colonoscopy
Colorectal cancer
colorectal cancer screening
Colorectal carcinoma
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - epidemiology
Compliance
Early Detection of Cancer
Emigration
Endoscopy
Feces
Female
Humans
Incidence
Italy
Male
Middle Aged
Mortality
Patient Compliance
Patients
Retrospective Studies
Risk Factors
Software
Survival Rate
Tumors
title Non-compliance with colonoscopy after a positive faecal immunochemical test doubles the risk of dying from colorectal cancer
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T17%3A30%3A31IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Non-compliance%20with%20colonoscopy%20after%20a%20positive%20faecal%20immunochemical%20test%20doubles%20the%20risk%20of%20dying%20from%20colorectal%20cancer&rft.jtitle=Gut&rft.au=Zorzi,%20Manuel&rft.date=2022-03-01&rft.volume=71&rft.issue=3&rft.spage=561&rft.epage=567&rft.pages=561-567&rft.issn=0017-5749&rft.eissn=1468-3288&rft_id=info:doi/10.1136/gutjnl-2020-322192&rft_dat=%3Cproquest_pubme%3E2507727300%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2626647275&rft_id=info:pmid/33789965&rfr_iscdi=true