Homology modeling and molecular docking simulation of martentoxin as a specific inhibitor of the BK channel

Large conductance calcium-activated potassium channel (BK channel) is gated by both voltage and calcium ions and is widely distributed in excitable and nonexcitable cells. BK channel plays an important role in epilepsy and other diseases, but BK channel subtype-specific drugs are still extremely rar...

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Veröffentlicht in:Annals of translational medicine 2022-01, Vol.10 (2), p.71-71
Hauptverfasser: Yang, Chao, Yang, Zihao, Tong, Kuiyuan, Wang, Jiawei, Yang, Wanli, Yu, Ruihua, Jiang, Feng, Ji, Yonghua
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Sprache:eng
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