Consensus for HER2 alterations testing in non-small-cell lung cancer

Human epidermal growth factor receptor 2 (HER2) is a transmembrane glycoprotein receptor with intracellular tyrosine kinase activity. Its alterations, including mutation, amplification and overexpression, could result in oncogenic potential and have been detected in many cancers such as non-small-ce...

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Veröffentlicht in:	ESMO open 2022-02, Vol.7 (1), p.100395-100395, Article 100395
Hauptverfasser:	Ren, S., Wang, J., Ying, J., Mitsudomi, T., Lee, D.H., Wang, Z., Chu, Q., Mack, P.C., Cheng, Y., Duan, J., Fan, Y., Han, B., Hui, Z., Liu, A., Liu, J., Lu, Y., Ma, Z., Shi, M., Shu, Y., Song, Q., Song, X., Song, Y., Wang, C., Wang, X., Xu, Y., Yao, Y., Zhang, L., Zhao, M., Zhu, B., Zhang, J., Zhou, C., Hirsch, F.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	amplification Carcinoma, Non-Small-Cell Lung - diagnosis Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology Consensus gene testing human epidermal growth factor receptor 2 Humans Lung Neoplasms - diagnosis Lung Neoplasms - drug therapy Lung Neoplasms - genetics Lung Neoplasms - pathology mutation non-small-cell lung cancer overexpression Receptor, ErbB-2 - genetics Receptor, ErbB-2 - therapeutic use Review
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