Hippocampal mTOR Dysregulation and Morphological Changes in Male Rats after Fetal Growth Restriction

Fetal growth restriction (FGR) has been linked to long-term neurocognitive impairment, especially in males. To determine possible underlying mechanisms, we examined hippocampal cellular composition and mTOR signaling of male rat FGR offspring during main brain growth and development (postnatal days...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nutrients 2022-01, Vol.14 (3), p.451
Hauptverfasser:	Schömig, Charlotte, Oberholz, Laura, Fink, Gregor, Voggel, Jenny, Wohlfarth, Maria, Dötsch, Jörg, Nüsken, Kai-Dietrich, Nüsken, Eva
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Animals Brain Cell density Cognition Cognitive ability Density Dentate gyrus Female Fetal Growth Retardation - etiology Fetuses Hippocampus Hippocampus - metabolism Long-term effects Low protein diet Male Males Malnutrition Memory Nutrient deficiency Offspring Phosphorylation Placenta Placenta - metabolism Placental Insufficiency Pregnancy Prenatal experience Protein synthesis Proteins Rats Sex differences Stress Surgery Tau protein TOR protein TOR Serine-Threonine Kinases - metabolism Uterus Veins & arteries
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!