The Protective Effects of Securigera securidaca Seed Extract on Liver Injury Induced by Bile Duct Ligation in Rats

This study is aimed at evaluating the effects of Securigera securidaca (SS) seed extract on cholestatic liver injury induced by bile duct ligation (BDL) in rats. Total polyphenols and flavonoids in SS seed extract were determined using a colorimetric assay, and their components were quantified using...

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Veröffentlicht in:	BioMed research international 2022-02, Vol.2022, p.6989963-12
Hauptverfasser:	Nasehi, Zahra, Kheiripour, Nejat, Taheri, Maryam Akhavan, Ardjmand, Abolfazl, Jozi, Faezeh, Aghadavod, Esmat, Doustimotlagh, Amir Hossein, Shahaboddin, Mohammad Esmaeil
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants Apoptosis Ascorbic acid Bile ducts Bilirubin Biomarkers - metabolism Carbonyl compounds Carbonyls Care and treatment Caspase-3 Catalase Cholestasis - drug therapy Chromatography, High Pressure Liquid Colorimetry Common bile duct Complications and side effects Disease Models, Animal Distilled water Drug dosages Enzymatic activity Enzyme activity Extracellular matrix Flavonoids Gallbladder diseases Genes Glutathione Health aspects High-performance liquid chromatography Inflammation Ligation Ligature (Surgery) Liquid chromatography Liver Liver diseases Male Malondialdehyde Medicinal plants Nitric oxide Nitric-oxide synthase Oxidative stress Parenchyma Patient outcomes Phenols Plant Extracts - chemistry Plant Extracts - pharmacology Polyphenols Proteins Rats Rats, Wistar Risk factors Securidaca Seeds Seeds - chemistry Serum levels Testing Vitamin C
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