Immunofluorescence and High-Resolution Microscopy Reveal New Insights in Human Globozoospermia

Globozoospermia is a rare and severe type of teratozoospermia characterized by the presence of round-headed, acrosomeless spermatozoa with cytoskeleton defects. Current data support a negative relationship between globozoospermia and intracytoplasmic sperm injection (ICSI) outcomes, revealing the ne...

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Veröffentlicht in:	International journal of molecular sciences 2022-02, Vol.23 (3), p.1729
Hauptverfasser:	Sáez-Espinosa, Paula, Robles-Gómez, Laura, Ortega-López, Leonor, Aizpurua, Jon, Gómez-Torres, María José
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers Cytoskeleton Electron microscopy Flagella Fluorescence Fluorescent Antibody Technique - methods Heat shock Heat shock proteins Humans Immunofluorescence Male Microscopy Microscopy, Electron, Scanning - methods Mitochondria Morphology Motility Patients Phosphorylation Reproduction Scanning electron microscopy Sperm Spermatozoa Spermatozoa - ultrastructure Structure-function relationships Teratozoospermia - diagnostic imaging Transmission electron microscopy Tubulin Tyrosine
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