Sex and Liver Disease: The Necessity of an Overarching Theory to Explain the Effect of Sex on Nonreproductive Functions

The number of studies illuminating major sex differences in liver metabolic activities is growing, but we still lack a theory to explain the origin of the functional differences we are identifying. In the animal kingdom, energy metabolism is tightly associated with reproduction; conceivably, the maj...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2022-01, Vol.163 (1), p.1
1. Verfasser:	Maggi, Adriana
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Biological Evolution Embryonic development Endocrinology Energy metabolism Energy storage Female Females Gender differences Gene Expression Regulation Gonadal Steroid Hormones - metabolism Humans Infants (Newborn) Lactation Liver Liver diseases Liver Diseases - genetics Liver Diseases - metabolism Male Males Mammals Metabolic Diseases - genetics Metabolic Diseases - metabolism Metabolism Mini-Review Nutrient deficiency Pharmacology Physiological aspects Reproductive status Sex differences Sex Factors Uterus Vertebrates Xenoestrogens
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