RCSB Protein Data Bank: improved annotation, search and visualization of membrane protein structures archived in the PDB

Abstract Motivation Membrane proteins are encoded by approximately one fifth of human genes but account for more than half of all US FDA approved drug targets. Thanks to new technological advances, the number of membrane proteins archived in the PDB is growing rapidly. However, automatic identificat...

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Veröffentlicht in:	Bioinformatics (Oxford, England) England), 2022-02, Vol.38 (5), p.1452-1454
Hauptverfasser:	Bittrich, Sebastian, Rose, Yana, Segura, Joan, Lowe, Robert, Westbrook, John D, Duarte, Jose M, Burley, Stephen K
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Applications Notes Databases, Protein Humans Membrane Proteins Protein Conformation Software
Online-Zugang:	Volltext
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