Dopamine depletion selectively disrupts interactions between striatal neuron subtypes and LFP oscillations

Dopamine degeneration in Parkinson's disease (PD) dysregulates the striatal neural network and causes motor deficits. However, it is unclear how altered striatal circuits relate to dopamine-acetylcholine chemical imbalance and abnormal local field potential (LFP) oscillations observed in PD. We...

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Veröffentlicht in:	Cell reports (Cambridge) 2022-01, Vol.38 (3), p.110265-110265, Article 110265
Hauptverfasser:	Zemel, Dana, Gritton, Howard, Cheung, Cyrus, Shankar, Sneha, Kramer, Mark, Han, Xue
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals basal ganglia beta oscillations Corpus Striatum - metabolism Corpus Striatum - physiopathology Dopamine - metabolism Female gamma oscillations immobility local field potential Locomotion - physiology Male Mice Neurons - metabolism Neurons - pathology Parkinson's disease Parkinsonian Disorders - metabolism Parkinsonian Disorders - physiopathology population dynamics striatum
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