Studies on Virulence and Extended-Spectrum β-Lactamase-Producing Uropathogenic Escherichia coli Isolates and Therapeutic Effect of Fosfomycin in Acute Pyelonephritis Mice

The understanding about virulence factors (VFs) and the drug resistance of uropathogenic Escherichia coli (UPEC) helps us understand the pathogenesis of urinary tract infections (UTIs) and make better decisions for clinical treatment. This study examined the correlation between the extended-spectrum...

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Veröffentlicht in:	BioMed research international 2022, Vol.2022 (1), p.8334153-8334153
Hauptverfasser:	Zhang, Lingchun, Li, Fenfen, Li, Xiaotian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics Bacteria beta-Lactamases Bladder Disease Models, Animal Drug resistance E coli Escherichia coli Escherichia coli Infections - drug therapy Escherichia coli Infections - microbiology Fosfomycin Fosfomycin - pharmacology Gene amplification Genes Gram-positive bacteria Histopathology Humans Inflammation Intravenous administration Kidneys Laboratory animals Mice Microbial Sensitivity Tests Pathogenesis Phenotypes Pili Pyelonephritis Pyelonephritis - drug therapy Pyelonephritis - microbiology Quality control Software Statistical analysis Strains (organisms) Structural integrity Urinary tract Urinary tract infections Urine Urogenital system Uropathogenic Escherichia coli - genetics Uropathogenic Escherichia coli - isolation & purification Uropathogenic Escherichia coli - pathogenicity Virulence Virulence - genetics Virulence factors β Lactamase
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