Synthesis, in silico study (DFT, ADMET) and crystal structure of novel sulfamoyloxy-oxazolidinones: Interaction with SARS-CoV-2

•10 derivatives of novel sulfamoyloxy-oxazolidinones were designed and synthesized.•The structure of the new compounds was confirmed using spectroscopy and spectrometry methods (IR, LC-MS, NMR and EA).•Molecular docking study was performed in order to evaluate synthesized compounds as possible inhib...

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Veröffentlicht in:	Journal of molecular structure 2022-06, Vol.1257, p.132579-132579, Article 132579
Hauptverfasser:	Bouzina, Abdeslem, Berredjem, Malika, Bouacida, Sofiane, Bachari, Khaldoun, Marminon, Christelle, Borgne, Marc Le, Bouaziz, Zouhair, Bouone, Yousra Ouafa
Format:	Artikel
Sprache:	eng
Schlagworte:	Crystal structure DFT study In silico study Molecular docking SARS-CoV-2 Sulfamoyloxy-oxazolidinone
Online-Zugang:	Volltext
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