Gm364 coordinates MIB2/DLL3/Notch2 to regulate female fertility through AKT activation

Many integral membrane proteins might act as indispensable coordinators in specific functional microdomains to maintain the normal operation of known receptors, such as Notch. Gm364 is a multi-pass transmembrane protein that has been screened as a potential female fertility factor. However, there ha...

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Veröffentlicht in:	Cell death and differentiation 2022-02, Vol.29 (2), p.366-380
Hauptverfasser:	Chen, Liang-Jian, Zhang, Na-Na, Zhou, Chun-Xiang, Yang, Zhi-Xia, Li, Yan-Ru, Zhang, Teng, Li, Cong-Rong, Wang, Xin, Wang, Yang, Wang, Zi-Bin, Xia, Zheng-Rong, Wang, Zhen-Bo, Zhang, Cui-Lian, Guan, Yi-Chun, Sun, Qing-Yuan, Zhang, Dong
Format:	Artikel
Sprache:	eng
Schlagworte:	101/58 13/1 13/95 14 14/1 14/28 38 38/91 631/80 64/60 692/308/1426 692/699/2732 82/51 82/80 82/83 96 AKT protein Aneuploidy Animals Apoptosis Biochemistry Biomedical and Life Sciences Cell Biology Cell Cycle Analysis Cytoplasm Female Fertility Follicles Integral membrane proteins Life Sciences Meiosis Membrane potential Membrane Proteins - metabolism Mitochondria Ovarian Follicle - metabolism Proto-Oncogene Proteins c-akt - metabolism Signal Transduction - physiology Stem Cells Ubiquitin Ubiquitin - metabolism Ubiquitin-protein ligase
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