Effects of imidazoline agents in a rat conditioned place preference model of addiction

Agmatine (AG), idazoxan (IDZ), and efaroxan (EFR) are imidazoline receptor ligands with beneficial effects in central nervous system disorders. The present study aimed to evaluate the interaction between AG, IDZ, and EFR with an opiate, tramadol (TR), in a conditioned place preference (CPP) paradigm...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology 2022-03, Vol.395 (3), p.365-376
Hauptverfasser:	Şorodoc, V., Rusu-Zota, G., Nechita, P., Moraru, C., Manole, O. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictions Agmatine Agmatine - pharmacology Analgesics, Opioid - pharmacology Animal models Animals Benzofurans - pharmacology Biomedical and Life Sciences Biomedicine Central nervous system Conditioning, Psychological - drug effects Drug Interactions Idazoxan - pharmacology Imidazoles - pharmacology Imidazoline Imidazoline Receptors - drug effects Imidazoline Receptors - metabolism Male Neurosciences Original Original Article Pharmacology/Toxicology Place preference conditioning Rats Rats, Wistar Rodents Statistics Time Factors Tramadol Tramadol - pharmacology
Online-Zugang:	Volltext
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