MiR-483 Promotes Colorectal Cancer Cell Biological Progression by Directly Targeting NDRG2 through Regulation of the PI3K/AKT Signaling Pathway and Epithelial-to-Mesenchymal Transition

Background. Colorectal cancer is the third frequent tumor in the whole world. MiR-483, located at the 11p15.5 locus, acts as an oncogene in multiple tumors. The purpose of this study is to explore the important roles of miR-483 in colorectal cancer. Materials and Methods. RT-qPCR and western blot we...

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Veröffentlicht in:	Journal of healthcare engineering 2022-01, Vol.2022, p.4574027-9
Hauptverfasser:	Sun, Xifeng, Li, Kun, Wang, Huiling, Xia, Yifang, Meng, Ping, Leng, Xiaogang
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Cell Movement - genetics Colorectal Neoplasms - genetics Humans MicroRNAs - genetics MicroRNAs - metabolism Phosphatidylinositol 3-Kinases - metabolism Proto-Oncogene Proteins c-akt - metabolism Signal Transduction - genetics Tumor Suppressor Proteins - metabolism
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