Exploring the limits of conventional small-scale CHO fed-batch for accelerated on demand monoclonal antibody production

In the field of therapeutic antibody production, diversification of fed-batch strategies is flourishing in response to the market demand. All manufacturing approaches tend to follow the generally accepted dogma of increasing titer since it directly increases manufacturing output. While titer is infl...

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Veröffentlicht in:Bioprocess and biosystems engineering 2022-02, Vol.45 (2), p.297-307
Hauptverfasser: Mahé, Amélie, Martiné, Alexandra, Fagète, Séverine, Girod, Pierre-Alain
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Sprache:eng
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