The Promise of Patient-Derived Colon Organoids to Model Ulcerative Colitis

Abstract Physiologic, molecular, and genetic findings all point to impaired intestinal epithelial function as a key element in the multifactorial pathogenesis of ulcerative colitis (UC). The lack of epithelial-directed therapies is a conspicuous weakness of our UC therapeutic armamentarium. However,...

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Veröffentlicht in:	Inflammatory bowel diseases 2022-02, Vol.28 (2), p.299-308
Hauptverfasser:	Ojo, Babajide A, VanDussen, Kelli L, Rosen, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic Science Review Colitis, Ulcerative Colon Humans Intestinal Mucosa Organoids Stem Cells
Online-Zugang:	Volltext
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