International consensus on the use of tau PET imaging agent 18F-flortaucipir in Alzheimer’s disease

Purpose Positron emission tomography (PET) with the first and only tau targeting radiotracer of 18 F-flortaucipir approved by FDA has been increasingly used in depicting tau pathology deposition and distribution in patients with cognitive impairment. The goal of this international consensus is to he...

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Veröffentlicht in:European journal of nuclear medicine and molecular imaging 2022-02, Vol.49 (3), p.895-904
Hauptverfasser: Tian, Mei, Civelek, A. Cahid, Carrio, Ignasi, Watanabe, Yasuyoshi, Kang, Keon Wook, Murakami, Koji, Garibotto, Valentina, Prior, John O., Barthel, Henryk, Zhou, Rui, Hou, Haifeng, Dou, Xiaofeng, Jin, Chentao, Zuo, Chuantao, Zhang, Hong
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container_end_page 904
container_issue 3
container_start_page 895
container_title European journal of nuclear medicine and molecular imaging
container_volume 49
creator Tian, Mei
Civelek, A. Cahid
Carrio, Ignasi
Watanabe, Yasuyoshi
Kang, Keon Wook
Murakami, Koji
Garibotto, Valentina
Prior, John O.
Barthel, Henryk
Zhou, Rui
Hou, Haifeng
Dou, Xiaofeng
Jin, Chentao
Zuo, Chuantao
Zhang, Hong
description Purpose Positron emission tomography (PET) with the first and only tau targeting radiotracer of 18 F-flortaucipir approved by FDA has been increasingly used in depicting tau pathology deposition and distribution in patients with cognitive impairment. The goal of this international consensus is to help nuclear medicine practitioners procedurally perform 18 F-flortaucipir PET imaging. Method A multidisciplinary task group formed by experts from various countries discussed and approved the consensus for 18 F-flortaucipir PET imaging in Alzheimer’s disease (AD), focusing on clinical scenarios, patient preparation, and administered activities, as well as image acquisition, processing, interpretation, and reporting. Conclusion This international consensus and practice guideline will help to promote the standardized use of 18 F-flortaucipir PET in patients with AD. It will become an international standard for this purpose in clinical practice.
doi_str_mv 10.1007/s00259-021-05673-w
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Cahid ; Carrio, Ignasi ; Watanabe, Yasuyoshi ; Kang, Keon Wook ; Murakami, Koji ; Garibotto, Valentina ; Prior, John O. ; Barthel, Henryk ; Zhou, Rui ; Hou, Haifeng ; Dou, Xiaofeng ; Jin, Chentao ; Zuo, Chuantao ; Zhang, Hong</creator><creatorcontrib>Tian, Mei ; Civelek, A. Cahid ; Carrio, Ignasi ; Watanabe, Yasuyoshi ; Kang, Keon Wook ; Murakami, Koji ; Garibotto, Valentina ; Prior, John O. ; Barthel, Henryk ; Zhou, Rui ; Hou, Haifeng ; Dou, Xiaofeng ; Jin, Chentao ; Zuo, Chuantao ; Zhang, Hong ; Molecular Imaging-based Precision Medicine Task Group of A3 (China-Japan-Korea) Foresight Program</creatorcontrib><description>Purpose Positron emission tomography (PET) with the first and only tau targeting radiotracer of 18 F-flortaucipir approved by FDA has been increasingly used in depicting tau pathology deposition and distribution in patients with cognitive impairment. The goal of this international consensus is to help nuclear medicine practitioners procedurally perform 18 F-flortaucipir PET imaging. Method A multidisciplinary task group formed by experts from various countries discussed and approved the consensus for 18 F-flortaucipir PET imaging in Alzheimer’s disease (AD), focusing on clinical scenarios, patient preparation, and administered activities, as well as image acquisition, processing, interpretation, and reporting. Conclusion This international consensus and practice guideline will help to promote the standardized use of 18 F-flortaucipir PET in patients with AD. It will become an international standard for this purpose in clinical practice.</description><identifier>ISSN: 1619-7070</identifier><identifier>EISSN: 1619-7089</identifier><identifier>DOI: 10.1007/s00259-021-05673-w</identifier><identifier>PMID: 34978595</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Alzheimer's disease ; Cardiology ; Cognitive ability ; Fluorine isotopes ; Guidelines ; Image acquisition ; Imaging ; Medical imaging ; Medicine ; Medicine &amp; Public Health ; Neurodegenerative diseases ; Neurology ; Nuclear Medicine ; Oncology ; Orthopedics ; Patients ; Positron emission ; Positron emission tomography ; Radioactive tracers ; Radiology ; Tau protein ; Tomography</subject><ispartof>European journal of nuclear medicine and molecular imaging, 2022-02, Vol.49 (3), p.895-904</ispartof><rights>The Author(s) 2022</rights><rights>The Author(s) 2022. 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Cahid</au><au>Carrio, Ignasi</au><au>Watanabe, Yasuyoshi</au><au>Kang, Keon Wook</au><au>Murakami, Koji</au><au>Garibotto, Valentina</au><au>Prior, John O.</au><au>Barthel, Henryk</au><au>Zhou, Rui</au><au>Hou, Haifeng</au><au>Dou, Xiaofeng</au><au>Jin, Chentao</au><au>Zuo, Chuantao</au><au>Zhang, Hong</au><aucorp>Molecular Imaging-based Precision Medicine Task Group of A3 (China-Japan-Korea) Foresight Program</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>International consensus on the use of tau PET imaging agent 18F-flortaucipir in Alzheimer’s disease</atitle><jtitle>European journal of nuclear medicine and molecular imaging</jtitle><stitle>Eur J Nucl Med Mol Imaging</stitle><date>2022-02-01</date><risdate>2022</risdate><volume>49</volume><issue>3</issue><spage>895</spage><epage>904</epage><pages>895-904</pages><issn>1619-7070</issn><eissn>1619-7089</eissn><abstract>Purpose Positron emission tomography (PET) with the first and only tau targeting radiotracer of 18 F-flortaucipir approved by FDA has been increasingly used in depicting tau pathology deposition and distribution in patients with cognitive impairment. The goal of this international consensus is to help nuclear medicine practitioners procedurally perform 18 F-flortaucipir PET imaging. Method A multidisciplinary task group formed by experts from various countries discussed and approved the consensus for 18 F-flortaucipir PET imaging in Alzheimer’s disease (AD), focusing on clinical scenarios, patient preparation, and administered activities, as well as image acquisition, processing, interpretation, and reporting. Conclusion This international consensus and practice guideline will help to promote the standardized use of 18 F-flortaucipir PET in patients with AD. It will become an international standard for this purpose in clinical practice.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>34978595</pmid><doi>10.1007/s00259-021-05673-w</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
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subjects Alzheimer's disease
Cardiology
Cognitive ability
Fluorine isotopes
Guidelines
Image acquisition
Imaging
Medical imaging
Medicine
Medicine & Public Health
Neurodegenerative diseases
Neurology
Nuclear Medicine
Oncology
Orthopedics
Patients
Positron emission
Positron emission tomography
Radioactive tracers
Radiology
Tau protein
Tomography
title International consensus on the use of tau PET imaging agent 18F-flortaucipir in Alzheimer’s disease
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