Elevated plasma levels of CXCL16 in severe COVID-19 patients

Genome-wide association studies have recently identified 3p21.31, with lead variant pointing to the CXCR6 gene, as the strongest thus far reported susceptibility risk locus for severe manifestation of COVID-19. In order the determine its role, we measured plasma levels of Chemokine (C‐X‐C motif) lig...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2022-04, Vol.152, p.155810-155810, Article 155810
Hauptverfasser:	Smieszek, Sandra P., Polymeropoulos, Vasilios M., Polymeropoulos, Christos M., Przychodzen, Bartlomiej P., Birznieks, Gunther, Polymeropoulos, Mihael H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Chemokine CXCL16 - blood Chemokine CXCL16 - genetics Chemokine CXCL16 - immunology COVID-19 COVID-19 - blood COVID-19 - genetics COVID-19 - immunology CXCL16 CXCR6 Female Humans Lung infection Male Middle Aged Patient Acuity Receptors, CXCR6 - blood Receptors, CXCR6 - genetics Receptors, CXCR6 - immunology SARS-CoV-2 - metabolism Signal Transduction - genetics Signal Transduction - immunology Whole genome sequencing
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