The Role of Oxidative Stress in the Pathogenesis of Vitiligo: A Culprit for Melanocyte Death

Vitiligo is a common chronic acquired pigmentation disorder characterized by loss of pigmentation. Among various hypotheses proposed for the pathogenesis of vitiligo, oxidative stress-induced immune response that ultimately leads to melanocyte death remains most widely accepted. Oxidative stress whi...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2022, Vol.2022, p.8498472-12
Hauptverfasser:	Xuan, Yijie, Yang, Yiwen, Xiang, Leihong, Zhang, Chengfeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidant Response Elements - genetics Antioxidants Apoptosis DNA damage Enzymes Homeostasis Humans Hypotheses Lipid peroxidation Lipids Melanocytes - cytology Melanocytes - metabolism Metabolism Metabolites NF-E2-Related Factor 2 - genetics NF-E2-Related Factor 2 - metabolism Oxidation Oxidative stress Oxidative Stress - genetics Pathogenesis Phospholipid Hydroperoxide Glutathione Peroxidase - genetics Phospholipid Hydroperoxide Glutathione Peroxidase - metabolism Proteins Reactive oxygen species Reactive Oxygen Species - metabolism Review Skin Vitiligo Vitiligo - metabolism Vitiligo - pathology
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