Tumor-associated antigen–specific T cells with nivolumab are safe and persist in vivo in relapsed/refractory Hodgkin lymphoma

Hodgkin lymphoma (HL) Reed Sternberg cells express tumor-associated antigens (TAA) that are potential targets for cellular therapies. We recently demonstrated that TAA-specific T cells (TAA-Ts) targeting WT1, PRAME, and Survivin were safe and associated with prolonged time to progression in solid tu...

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Veröffentlicht in:	Blood advances 2022-01, Vol.6 (2), p.473-485
Hauptverfasser:	Dave, Hema, Terpilowski, Madeline, Mai, Mimi, Toner, Keri, Grant, Melanie, Stanojevic, Maja, Lazarski, Christopher, Shibli, Abeer, Bien, Stephanie A., Maglo, Philip, Hoq, Fahmida, Schore, Reuven, Glenn, Martha, Hu, Boyu, Hanley, Patrick J., Ambinder, Richard, Bollard, Catherine M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm Clinical Trials and Observations Disease Progression Hodgkin Disease - drug therapy Humans Nivolumab - therapeutic use T-Lymphocytes - pathology
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