Noninsect-Based Diet Leads to Structural and Functional Changes of Acidic Chitinase in Carnivora

Abstract Acidic chitinase (Chia) digests the chitin of insects in the omnivorous stomach and the chitinase activity in carnivorous Chia is significantly lower than that of the omnivorous enzyme. However, mechanistic and evolutionary insights into the functional changes in Chia remain unclear. Here w...

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Veröffentlicht in:Molecular biology and evolution 2022-01, Vol.39 (1)
Hauptverfasser: Tabata, Eri, Itoigawa, Akihiro, Koinuma, Takumi, Tayama, Hiroshi, Kashimura, Akinori, Sakaguchi, Masayoshi, Matoska, Vaclav, Bauer, Peter O, Oyama, Fumitaka
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