Anti-cryptococcal activity of preussolides A and B, phosphoethanolamine-substituted 24-membered macrolides, and leptosin C from coprophilous isolates of Preussia typharum

Cryptococcus neoformans is a serious human pathogen with limited options for treatment. We have interrogated extracts from fungal fermentations to find Cryptococcus-inhibiting natural products using assays for growth inhibition and differential thermosensitivity. Extracts from fermentations of four...

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Veröffentlicht in:	Journal of industrial microbiology & biotechnology 2021-12, Vol.48 (9-10), p.1
Hauptverfasser:	Perlatti, Bruno, Lan, Nan, Xiang, Meichun, Earp, Cody E, Spraker, Joseph E, Harvey, Colin J B, Nichols, Connie B, Alspaugh, J Andrew, Gloer, James B, Bills, Gerald F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antifungal Agents - pharmacology Ascomycota BCG BCG vaccines Cryptococcus neoformans DNA sequencing Ethanolamines Fermentation Genomics Humans Indole Alkaloids Macrolides - pharmacology Metabolites Natural Products Nucleotide sequencing Physiological aspects
Online-Zugang:	Volltext
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