A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in mice

Since the beginning of the COVID-19 pandemic, the development of effective vaccines against this pathogen has been a priority for the scientific community. Several strategies have been developed including vaccines based on recombinant viral protein fragments. The receptor-binding domain (RBD) in the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2022-02, Vol.40 (8), p.1162-1169
Hauptverfasser:	Lazo, Laura, Bequet-Romero, Monica, Lemos, Gilda, Musacchio, Alexis, Cabrales, Ania, Bruno, Andy J., Ariel Espinosa, Luis, Saloheimo, Markku, Vitikainen, Marika, Hernández, Amalia, Emalfarb, Mark, Tchelet, Ronen, Suzarte, Edith, Guillén, Gerardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Antibodies Antibodies, Neutralizing Antibodies, Viral Binding Biotechnology Core protein Coronaviruses COVID COVID-19 COVID-19 infection COVID-19 Vaccines Disease transmission Enzymes Fungi Genetic engineering Hepatitis B Hepatitis B virus HIV Human immunodeficiency virus Humans Immune response Immune response (cell-mediated) Immune response (humoral) Immune system Immunity, Cellular Immunogenicity Mice Mice, Inbred BALB C Pandemics pathogens Protein Proteins Public health Receptors SARS CoV-2 Severe acute respiratory syndrome coronavirus 2 Spike Glycoprotein, Coronavirus Vaccine Vaccines Viral diseases
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!