Osteoporosis Can Be the Sole Presentation in Celiac Disease

Osteoporosis Can Be the Sole Presentation in Celiac Disease

Celiac disease, an autoimmune condition causing gluten intolerance and disrupted absorption of nutrients, predisposes to osteoporosis. The release of pro-inflammatory cytokines, calcium malabsorption, and the activation of osteoclasts represent the main mechanisms responsible for bone derangement. T...

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Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2021-12, Vol.13 (12), p.e20602
Hauptverfasser: Bommu, Veera Jayasree Latha, Mirza, Lubna
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Endocrinology/Diabetes/Metabolism
Gastroenterology
Internal Medicine
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Mirza, Lubna
description Celiac disease, an autoimmune condition causing gluten intolerance and disrupted absorption of nutrients, predisposes to osteoporosis. The release of pro-inflammatory cytokines, calcium malabsorption, and the activation of osteoclasts represent the main mechanisms responsible for bone derangement. This is evidenced by the low T-score on dual-energy x-ray absorptiometry (DXA) scans in these patients. However, these changes are reversible with the early initiation of a gluten-free diet. Hence, it is important for physicians to consider screening for celiac disease panel in patients presenting with osteoporotic features with no clear etiology.
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subjects Endocrinology/Diabetes/Metabolism
Gastroenterology
Internal Medicine
title Osteoporosis Can Be the Sole Presentation in Celiac Disease
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