Management of altered metabolic activity in Drosophila model of Huntington’s disease by curcumin

Huntington’s disease (HD) is a devastating polyglutamine disorder characterized by extensive neurodegeneration and metabolic abnormalities at systemic, cellular and intracellular levels. Metabolic alterations in HD manifest as abnormal body weight, dysregulated biomolecule levels, impaired adipocyte...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2022-01, Vol.247 (2), p.152-164
Hauptverfasser:	Aditi, Kumari, Singh, Akanksha, Shakarad, Mallikarjun N, Agrawal, Namita
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - metabolism Animals Carbohydrate Metabolism - drug effects Curcumin - pharmacology Disease Models, Animal Drosophila melanogaster Humans Huntington Disease - drug therapy Huntington Disease - metabolism Lipid Metabolism - drug effects Original Research Reactive Oxygen Species - metabolism
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