COVID-19 lockdown impact on mental health in a large representative sample of Italian adults
•This is the first cross-sectional multi-disciplinary consortium study conducted in Italy on a representative sample of adults to testify the huge implications of the COVID-19 lockdown on mental health.•National-level prevalence of depressive and anxiety symptoms doubled, getting to affect more than...
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| Veröffentlicht in: | Journal of affective disorders 2021-09, Vol.292, p.398-404 |
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| creator | Amerio, Andrea Lugo, Alessandra Stival, Chiara Fanucchi, Tiziana Gorini, Giuseppe Pacifici, Roberta Odone, Anna Serafini, Gianluca Gallus, Silvano |
| description | •This is the first cross-sectional multi-disciplinary consortium study conducted in Italy on a representative sample of adults to testify the huge implications of the COVID-19 lockdown on mental health.•National-level prevalence of depressive and anxiety symptoms doubled, getting to affect more than one third of the general adult population and the use of at least one psychotropic drug – mostly anxiolytics/benzodiazepines – increased by 20%.•Women more frequently worsened their mental health, as compared to men.•A worsening in depressive symptoms was more likely observed in young, in current and former smokers, in gamblers, and in subjects reporting longer time spent outdoor and more hours of physical activity before the lockdown.
The potential benefits of the COVID-19 lockdown need to be carefully weighed versus the possible impact on people's daily life and negative mental health effects.We aimed to assess the prevalence of depression, anxiety, insomnia and quality of life before and during the COVID-19 lockdown,identifying subgroups at higher risk of mental distress as a consequence of COVID-19 associated restrictions.
Within the Lost in Italy project, a web-based cross-sectional study was conducted on a representative sample of 6003 Italian adults aged 18–74 recruited from April 27 to May 3, 2020, within the nation-wide stay-at-home order.
The prevalence of depressive symptoms (PHQ-2 ≥ 3) increased from 14.3% before lockdown to 33.2% during lockdown, anxiety symptoms (GAD-2 ≥ 3) from 18.1% to 41.5%, insufficient sleep (≤6 h/day) from 33.7% to 41.1%, unsatisfactory sleep from 17.0% to 38.8% and unsatisfactory quality of life from 13.1% to 42.1%.Overall, 47.7% reported worsened depressive symptoms, 43.6% worsened anxiety symptoms, sleep quantity (31.5%) and quality (35.0%),and 64.1% worsened quality of life.A statistically significant relationship with all mental health outcomes considered was found for women vs. men (multivariate odds ratio,OR between 1.13 and 1.63), for current vs. never smokers (OR between 1.15 and 1.25), and with increasing physical activity (p for trend |
| doi_str_mv | 10.1016/j.jad.2021.05.117 |
| format | Article |
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The potential benefits of the COVID-19 lockdown need to be carefully weighed versus the possible impact on people's daily life and negative mental health effects.We aimed to assess the prevalence of depression, anxiety, insomnia and quality of life before and during the COVID-19 lockdown,identifying subgroups at higher risk of mental distress as a consequence of COVID-19 associated restrictions.
Within the Lost in Italy project, a web-based cross-sectional study was conducted on a representative sample of 6003 Italian adults aged 18–74 recruited from April 27 to May 3, 2020, within the nation-wide stay-at-home order.
The prevalence of depressive symptoms (PHQ-2 ≥ 3) increased from 14.3% before lockdown to 33.2% during lockdown, anxiety symptoms (GAD-2 ≥ 3) from 18.1% to 41.5%, insufficient sleep (≤6 h/day) from 33.7% to 41.1%, unsatisfactory sleep from 17.0% to 38.8% and unsatisfactory quality of life from 13.1% to 42.1%.Overall, 47.7% reported worsened depressive symptoms, 43.6% worsened anxiety symptoms, sleep quantity (31.5%) and quality (35.0%),and 64.1% worsened quality of life.A statistically significant relationship with all mental health outcomes considered was found for women vs. men (multivariate odds ratio,OR between 1.13 and 1.63), for current vs. never smokers (OR between 1.15 and 1.25), and with increasing physical activity (p for trend<0.001 for all the indicators).The use of at least one psychotropic drug increased by 20% compared to pre-lockdown (from 9.5% to 11.4%).
This is the first cross-sectional study conducted in Italy on a representative sample of adults to testify the huge implications of the lockdown on mental health.</description><identifier>ISSN: 0165-0327</identifier><identifier>EISSN: 1573-2517</identifier><identifier>DOI: 10.1016/j.jad.2021.05.117</identifier><identifier>PMID: 34139414</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Adult ; Anxiety - epidemiology ; Communicable Disease Control ; COVID-19 ; Cross-Sectional Studies ; Depression - epidemiology ; Female ; Humans ; Italy - epidemiology ; Lost in italy ; Male ; Mental Health ; Quality of Life ; Representative survey ; Research Paper ; SARS-CoV-2</subject><ispartof>Journal of affective disorders, 2021-09, Vol.292, p.398-404</ispartof><rights>2021</rights><rights>Copyright © 2021. Published by Elsevier B.V.</rights><rights>2021 Elsevier B.V. All rights reserved. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c565t-969430932cce90d81a3aaace6da652ccb1164154cda418e1e0ba171eb11e88993</citedby><cites>FETCH-LOGICAL-c565t-969430932cce90d81a3aaace6da652ccb1164154cda418e1e0ba171eb11e88993</cites><orcidid>0000-0002-6722-7109 ; 0000-0002-5657-9774 ; 0000-0002-3439-340X ; 0000-0002-8967-0400 ; 0000-0002-4297-6496</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0165032721005632$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34139414$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Amerio, Andrea</creatorcontrib><creatorcontrib>Lugo, Alessandra</creatorcontrib><creatorcontrib>Stival, Chiara</creatorcontrib><creatorcontrib>Fanucchi, Tiziana</creatorcontrib><creatorcontrib>Gorini, Giuseppe</creatorcontrib><creatorcontrib>Pacifici, Roberta</creatorcontrib><creatorcontrib>Odone, Anna</creatorcontrib><creatorcontrib>Serafini, Gianluca</creatorcontrib><creatorcontrib>Gallus, Silvano</creatorcontrib><title>COVID-19 lockdown impact on mental health in a large representative sample of Italian adults</title><title>Journal of affective disorders</title><addtitle>J Affect Disord</addtitle><description>•This is the first cross-sectional multi-disciplinary consortium study conducted in Italy on a representative sample of adults to testify the huge implications of the COVID-19 lockdown on mental health.•National-level prevalence of depressive and anxiety symptoms doubled, getting to affect more than one third of the general adult population and the use of at least one psychotropic drug – mostly anxiolytics/benzodiazepines – increased by 20%.•Women more frequently worsened their mental health, as compared to men.•A worsening in depressive symptoms was more likely observed in young, in current and former smokers, in gamblers, and in subjects reporting longer time spent outdoor and more hours of physical activity before the lockdown.
The potential benefits of the COVID-19 lockdown need to be carefully weighed versus the possible impact on people's daily life and negative mental health effects.We aimed to assess the prevalence of depression, anxiety, insomnia and quality of life before and during the COVID-19 lockdown,identifying subgroups at higher risk of mental distress as a consequence of COVID-19 associated restrictions.
Within the Lost in Italy project, a web-based cross-sectional study was conducted on a representative sample of 6003 Italian adults aged 18–74 recruited from April 27 to May 3, 2020, within the nation-wide stay-at-home order.
The prevalence of depressive symptoms (PHQ-2 ≥ 3) increased from 14.3% before lockdown to 33.2% during lockdown, anxiety symptoms (GAD-2 ≥ 3) from 18.1% to 41.5%, insufficient sleep (≤6 h/day) from 33.7% to 41.1%, unsatisfactory sleep from 17.0% to 38.8% and unsatisfactory quality of life from 13.1% to 42.1%.Overall, 47.7% reported worsened depressive symptoms, 43.6% worsened anxiety symptoms, sleep quantity (31.5%) and quality (35.0%),and 64.1% worsened quality of life.A statistically significant relationship with all mental health outcomes considered was found for women vs. men (multivariate odds ratio,OR between 1.13 and 1.63), for current vs. never smokers (OR between 1.15 and 1.25), and with increasing physical activity (p for trend<0.001 for all the indicators).The use of at least one psychotropic drug increased by 20% compared to pre-lockdown (from 9.5% to 11.4%).
This is the first cross-sectional study conducted in Italy on a representative sample of adults to testify the huge implications of the lockdown on mental health.</description><subject>Adult</subject><subject>Anxiety - epidemiology</subject><subject>Communicable Disease Control</subject><subject>COVID-19</subject><subject>Cross-Sectional Studies</subject><subject>Depression - epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Italy - epidemiology</subject><subject>Lost in italy</subject><subject>Male</subject><subject>Mental Health</subject><subject>Quality of Life</subject><subject>Representative survey</subject><subject>Research Paper</subject><subject>SARS-CoV-2</subject><issn>0165-0327</issn><issn>1573-2517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kN1qGzEQRkVJqJ20D9CboBfYjWZ3tVpRKAQnbQyB3KS9KoixNLbl7B_SxiFvHxm3ob3JlWDmfJ-kw9gXEDkIqC93-Q5dXogCciFzAPWBzUGqMiskqBM2T4zMRFmoGTuLcSeEqLUSH9msrKDUFVRz9ntx_2t5nYHm7WAf3fDcc9-NaCc-9LyjfsKWbwnbact9z5G3GDbEA42B4mE7-T3xiN3YEh_WfJl4jwl0T-0UP7HTNbaRPv85z9nP7zcPi9vs7v7HcnF1l1lZyynTta5KocvCWtLCNYAlIlqqHdYyDVcAdQWysg4raAhIrBAUUJpT02hdnrNvx97xadWRs-lhAVszBt9heDEDevP_pvdbsxn2plFKiVqmAjgW2DDEGGj9lgVhDqrNziTV5qDaCGmS6pS5-PfSt8Rftwn4egQofX3vKZhoPfWWnA9kJ-MG_079K_C3kC8</recordid><startdate>20210901</startdate><enddate>20210901</enddate><creator>Amerio, Andrea</creator><creator>Lugo, Alessandra</creator><creator>Stival, Chiara</creator><creator>Fanucchi, Tiziana</creator><creator>Gorini, Giuseppe</creator><creator>Pacifici, Roberta</creator><creator>Odone, Anna</creator><creator>Serafini, Gianluca</creator><creator>Gallus, Silvano</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6722-7109</orcidid><orcidid>https://orcid.org/0000-0002-5657-9774</orcidid><orcidid>https://orcid.org/0000-0002-3439-340X</orcidid><orcidid>https://orcid.org/0000-0002-8967-0400</orcidid><orcidid>https://orcid.org/0000-0002-4297-6496</orcidid></search><sort><creationdate>20210901</creationdate><title>COVID-19 lockdown impact on mental health in a large representative sample of Italian adults</title><author>Amerio, Andrea ; Lugo, Alessandra ; Stival, Chiara ; Fanucchi, Tiziana ; Gorini, Giuseppe ; Pacifici, Roberta ; Odone, Anna ; Serafini, Gianluca ; Gallus, Silvano</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c565t-969430932cce90d81a3aaace6da652ccb1164154cda418e1e0ba171eb11e88993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Anxiety - epidemiology</topic><topic>Communicable Disease Control</topic><topic>COVID-19</topic><topic>Cross-Sectional Studies</topic><topic>Depression - epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Italy - epidemiology</topic><topic>Lost in italy</topic><topic>Male</topic><topic>Mental Health</topic><topic>Quality of Life</topic><topic>Representative survey</topic><topic>Research Paper</topic><topic>SARS-CoV-2</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Amerio, Andrea</creatorcontrib><creatorcontrib>Lugo, Alessandra</creatorcontrib><creatorcontrib>Stival, Chiara</creatorcontrib><creatorcontrib>Fanucchi, Tiziana</creatorcontrib><creatorcontrib>Gorini, Giuseppe</creatorcontrib><creatorcontrib>Pacifici, Roberta</creatorcontrib><creatorcontrib>Odone, Anna</creatorcontrib><creatorcontrib>Serafini, Gianluca</creatorcontrib><creatorcontrib>Gallus, Silvano</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of affective disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Amerio, Andrea</au><au>Lugo, Alessandra</au><au>Stival, Chiara</au><au>Fanucchi, Tiziana</au><au>Gorini, Giuseppe</au><au>Pacifici, Roberta</au><au>Odone, Anna</au><au>Serafini, Gianluca</au><au>Gallus, Silvano</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>COVID-19 lockdown impact on mental health in a large representative sample of Italian adults</atitle><jtitle>Journal of affective disorders</jtitle><addtitle>J Affect Disord</addtitle><date>2021-09-01</date><risdate>2021</risdate><volume>292</volume><spage>398</spage><epage>404</epage><pages>398-404</pages><issn>0165-0327</issn><eissn>1573-2517</eissn><abstract>•This is the first cross-sectional multi-disciplinary consortium study conducted in Italy on a representative sample of adults to testify the huge implications of the COVID-19 lockdown on mental health.•National-level prevalence of depressive and anxiety symptoms doubled, getting to affect more than one third of the general adult population and the use of at least one psychotropic drug – mostly anxiolytics/benzodiazepines – increased by 20%.•Women more frequently worsened their mental health, as compared to men.•A worsening in depressive symptoms was more likely observed in young, in current and former smokers, in gamblers, and in subjects reporting longer time spent outdoor and more hours of physical activity before the lockdown.
The potential benefits of the COVID-19 lockdown need to be carefully weighed versus the possible impact on people's daily life and negative mental health effects.We aimed to assess the prevalence of depression, anxiety, insomnia and quality of life before and during the COVID-19 lockdown,identifying subgroups at higher risk of mental distress as a consequence of COVID-19 associated restrictions.
Within the Lost in Italy project, a web-based cross-sectional study was conducted on a representative sample of 6003 Italian adults aged 18–74 recruited from April 27 to May 3, 2020, within the nation-wide stay-at-home order.
The prevalence of depressive symptoms (PHQ-2 ≥ 3) increased from 14.3% before lockdown to 33.2% during lockdown, anxiety symptoms (GAD-2 ≥ 3) from 18.1% to 41.5%, insufficient sleep (≤6 h/day) from 33.7% to 41.1%, unsatisfactory sleep from 17.0% to 38.8% and unsatisfactory quality of life from 13.1% to 42.1%.Overall, 47.7% reported worsened depressive symptoms, 43.6% worsened anxiety symptoms, sleep quantity (31.5%) and quality (35.0%),and 64.1% worsened quality of life.A statistically significant relationship with all mental health outcomes considered was found for women vs. men (multivariate odds ratio,OR between 1.13 and 1.63), for current vs. never smokers (OR between 1.15 and 1.25), and with increasing physical activity (p for trend<0.001 for all the indicators).The use of at least one psychotropic drug increased by 20% compared to pre-lockdown (from 9.5% to 11.4%).
This is the first cross-sectional study conducted in Italy on a representative sample of adults to testify the huge implications of the lockdown on mental health.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>34139414</pmid><doi>10.1016/j.jad.2021.05.117</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-6722-7109</orcidid><orcidid>https://orcid.org/0000-0002-5657-9774</orcidid><orcidid>https://orcid.org/0000-0002-3439-340X</orcidid><orcidid>https://orcid.org/0000-0002-8967-0400</orcidid><orcidid>https://orcid.org/0000-0002-4297-6496</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of affective disorders, 2021-09, Vol.292, p.398-404 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Anxiety - epidemiology Communicable Disease Control COVID-19 Cross-Sectional Studies Depression - epidemiology Female Humans Italy - epidemiology Lost in italy Male Mental Health Quality of Life Representative survey Research Paper SARS-CoV-2 |
| title | COVID-19 lockdown impact on mental health in a large representative sample of Italian adults |
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