Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors

Black men die from prostate cancer twice as often as White men, a disparity likely due to inherited genetics, modifiable cancer risk factors, and healthcare access. It is incompletely understood how and why tumor genomes differ by self-reported race and genetic ancestry. Among 2,069 men with prostat...

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Veröffentlicht in:	Clinical cancer research 2022-01, Vol.28 (2), p.318-326
Hauptverfasser:	Stopsack, Konrad H, Nandakumar, Subhiksha, Arora, Kanika, Nguyen, Bastien, Vasselman, Samantha E, Nweji, Barbara, McBride, Sean M, Morris, Michael J, Rathkopf, Dana E, Slovin, Susan F, Danila, Daniel C, Autio, Karen A, Scher, Howard I, Mucci, Lorelei A, Solit, David B, Gönen, Mithat, Chen, Yu, Berger, Michael F, Schultz, Nikolaus, Abida, Wassim, Kantoff, Philip W
Format:	Artikel
Sprache:	eng
Schlagworte:	Blacks Humans Male Prostatic Neoplasms - diagnosis Prostatic Neoplasms - epidemiology Prostatic Neoplasms - genetics Risk Factors Self Report Whites
Online-Zugang:	Volltext
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