Association between pre-diagnostic circulating adipokines and colorectal cancer and adenoma in the CLUE II cohort

Objective Obesity is a known risk factor for colorectal cancer (CRC) and adenoma. Obese individuals have higher circulating concentrations of certain endocrine and immune factors produced by adipocytes thought to partially underlie the association between obesity and colorectal neoplasia. Thus, we e...

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Veröffentlicht in:	Cancer causes & control 2021-08, Vol.32 (8), p.871-881
Hauptverfasser:	Marrone, Michael T., Lu, Jiayun, Visvanathan, Kala, Joshu, Corinne E., Platz, Elizabeth A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma Adenoma - blood Adipocytes Adipokines - blood Adiponectin Adiponectin - blood Aged Biomarkers - blood Biomedical and Life Sciences Biomedicine Cancer Cancer Research Carcinogenesis Carcinogens Case-Control Studies Cohort Studies Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnosis Confidence intervals Endoscopy Epidemiology Female Hematology Humans Leptin Leptin - blood Male Markers Medical diagnosis Middle Aged Obesity Obesity - complications Oncology ORIGINAL PAPER Prospective Studies Public Health Quartiles Risk analysis Risk Factors Statistical analysis Tumor Necrosis Factor-alpha - blood Tumor necrosis factor-TNF Tumor necrosis factor-α Tumors
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