GLP-1a: Going beyond Traditional Use

Glucagon-like peptide-1 (GLP-1) is a human incretin hormone derived from the proglucagon molecule. GLP-1 receptor agonists are frequently used to treat type 2 diabetes mellitus and obesity. However, the hormone affects the liver, pancreas, brain, fat cells, heart, and gastrointestinal tract. The obj...

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Veröffentlicht in:	International journal of molecular sciences 2022-01, Vol.23 (2), p.739
Hauptverfasser:	Laurindo, Lucas Fornari, Barbalho, Sandra Maria, Guiguer, Elen Landgraf, da Silva Soares de Souza, Maricelma, de Souza, Gabriela Achete, Fidalgo, Thiago Marques, Araújo, Adriano Cressoni, de Souza Gonzaga, Heron F, de Bortoli Teixeira, Daniel, de Oliveira Silva Ullmann, Thais, Sloan, Katia Portero, Sloan, Lance Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipose tissue Agonists Alzheimer's disease Analogs Apoptosis Appetite Blood-brain barrier Body fat Body mass index Clinical medicine Clinical trials Clinical Trials as Topic Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - drug therapy Disease Management Dopamine receptors Drug dosages Enzymes Fatty liver Gastrointestinal system Gastrointestinal tract GLP-1 receptor agonists Glucagon Glucagon-like peptide 1 Glucagon-Like Peptide 1 - metabolism Glucagon-Like Peptide 1 - pharmacology Glucagon-Like Peptide 1 - therapeutic use Glucagon-Like Peptide-1 Receptor - agonists Glucose Glucose metabolism Glucose transport Hepatocytes Homeostasis Humans Hyperglycemia Inhibition (psychology) Insulin Insulin resistance Liver Liver diseases Metabolism Neurodegenerative Diseases - drug therapy Obesity Obesity - drug therapy Pancreas Parkinson's disease Peptide Fragments - metabolism Peptide Fragments - pharmacology Peptide Fragments - therapeutic use Psoriasis Quality of life Reinforcement Review Systematic review Treatment Outcome Weight control Well being
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