Lysine Acetylation, Cancer Hallmarks and Emerging Onco-Therapeutic Opportunities

Acetylation, a reversible epigenetic process, is implicated in many critical cellular regulatory systems including transcriptional regulation, protein structure, activity, stability, and localization. Lysine acetylation is the most prevalent and intensively investigated among the diverse acetylation...

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Veröffentlicht in:	Cancers 2022-01, Vol.14 (2), p.346
Hauptverfasser:	Hu, Meilan, He, Fule, Thompson, Erik W, Ostrikov, Kostya Ken, Dai, Xiaofeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Apoptosis Cancer Cell cycle Cell division Cytoplasm Drug development Epigenetics Gene regulation Genes Genomes Histone deacetylase Localization Lysine Metabolic disorders Metabolism Metastasis Mitochondria Protein structure Proteins Review RNA polymerase Roles Signal transduction Transcription Tumor cells
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