Role of Slit/Robo Signaling pathway in Bone Metabolism

Slit/Robo signals were initially found to play an essential role in nerve development as axonal guidance molecules. In recent years, with in-depth study, the role of Slit/Robo in other life activities, such as tumor development, angiogenesis, cell migration, and bone homeostasis, has gradually been...

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Veröffentlicht in:	International journal of biological sciences 2022-01, Vol.18 (3), p.1303-1312
Hauptverfasser:	Jiang, Lingyu, Sun, Jianxun, Huang, Dingming
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Axon guidance Axonogenesis Bone diseases Bone growth Bone Resorption Bone tumors Bone turnover Cell adhesion & migration Cell growth Cell migration Cell Movement Chromosomes Coupling (molecular) Epidermal growth factor Extracellular matrix Genes Homeostasis Humans Immunoglobulins Insects Ligands Metabolism Molecular structure Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Nervous system Osteogenesis Proteins Receptors, Immunologic - metabolism Review Robo protein Signal Transduction Signaling Slit protein
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