Therapeutic Potential of Senolytics in Cardiovascular Disease

Ageing is the biggest risk factor for impaired cardiovascular health, with cardiovascular disease being the leading cause of death in 40% of individuals over 65 years old. Ageing is associated with both an increased prevalence of cardiovascular disease including heart failure, coronary artery diseas...

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Veröffentlicht in:	Cardiovascular drugs and therapy 2022-02, Vol.36 (1), p.187-196
Hauptverfasser:	Dookun, Emily, Passos, João F., Arthur, Helen M., Richardson, Gavin D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging Animals Apoptosis Apoptosis - drug effects Atherosclerosis Cardiology Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - drug therapy Cardiovascular Diseases - physiopathology Cellular Senescence - drug effects Congestive heart failure Coronary artery Coronary artery disease Disease Progression Health risks Humans Inflammation Invited Review Invited Review Article Medicine Medicine & Public Health Myocardial infarction Pathophysiology Phenotypes Prognosis Risk analysis Risk Factors Senescence Senescence-Associated Secretory Phenotype - physiology Senotherapeutics - pharmacology
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