Comparative analysis of the pregnancy rate via in vitro fertilization vs. previous artificial insemination in patients with unexplained infertility
To compare the clinical pregnancy rate among patients undergoing direct in vitro fertilization vs. in vitro fertilization after two cycles of intrauterine insemination in couples with unexplained infertility. Comparative cross-sectional, retrospective study from 2016 to 2019, from the Centro Mexican...
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| Veröffentlicht in: | JBRA assisted reproduction 2022-01, Vol.26 (1), p.22-27 |
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| creator | Mendieta, Maitane Alonso de Aranda, Alejandro Sánchez López, Juan Francisco Molina Sánchez, Armando Miguel Roque Mondragón, Esperanza Carballo Monterrosas, Leonor Ángela Durán Ambe, Alberto Kably |
| description | To compare the clinical pregnancy rate among patients undergoing direct in vitro fertilization vs. in vitro fertilization after two cycles of intrauterine insemination in couples with unexplained infertility.
Comparative cross-sectional, retrospective study from 2016 to 2019, from the Centro Mexicano de Fertilidad Doctor Alberto Kably. The patients with unexplained infertility were divided into two groups, direct in vitro fertilization and a group of in vitro fertilization after intrauterine insemination, and we compared the rate of pregnancy and live births in both cases.
89 couples with unexplained infertility were included, the in vitro fertilization after intrauterine insemination group (n=46) and direct in vitro fertilization group (n=43). The direct in vitro fertilization group resulted in a higher clinical pregnancy rate throughout the study compared to the other group (55.8% vs. 34.8%, OR 2.37; 95% CI 1.008 - 5.57, p=0.046). However, there was no difference in the rate of live newborns (p=0.12). When analyzing the data by cycle, we noticed a statistical difference in both, the clinical pregnancy rate in the direct in vitro fertilization group (38.7% vs. 16.7%, OR 3.2; 95% CI 1.50-6.62), as well as the rate of live newborns (32.3 % vs. 14.6%, OR 2.79; 95% CI 1.28-6.07, p=0.008).
In the in vitro fertilization group, as first-line treatment for unexplained infertility, the patients had a higher pregnancy rate. |
| doi_str_mv | 10.5935/1518-0557.20210038 |
| format | Article |
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Comparative cross-sectional, retrospective study from 2016 to 2019, from the Centro Mexicano de Fertilidad Doctor Alberto Kably. The patients with unexplained infertility were divided into two groups, direct in vitro fertilization and a group of in vitro fertilization after intrauterine insemination, and we compared the rate of pregnancy and live births in both cases.
89 couples with unexplained infertility were included, the in vitro fertilization after intrauterine insemination group (n=46) and direct in vitro fertilization group (n=43). The direct in vitro fertilization group resulted in a higher clinical pregnancy rate throughout the study compared to the other group (55.8% vs. 34.8%, OR 2.37; 95% CI 1.008 - 5.57, p=0.046). However, there was no difference in the rate of live newborns (p=0.12). When analyzing the data by cycle, we noticed a statistical difference in both, the clinical pregnancy rate in the direct in vitro fertilization group (38.7% vs. 16.7%, OR 3.2; 95% CI 1.50-6.62), as well as the rate of live newborns (32.3 % vs. 14.6%, OR 2.79; 95% CI 1.28-6.07, p=0.008).
In the in vitro fertilization group, as first-line treatment for unexplained infertility, the patients had a higher pregnancy rate.</description><identifier>ISSN: 1518-0557</identifier><identifier>ISSN: 1517-5693</identifier><identifier>EISSN: 1518-0557</identifier><identifier>DOI: 10.5935/1518-0557.20210038</identifier><identifier>PMID: 34415121</identifier><language>eng</language><publisher>Brazil: Sociedade Brasileira de Reprodução Humana (Brazilian Society of Assisted Reproduction)</publisher><subject>Age ; Cross-Sectional Studies ; Female ; Fertility ; Fertilization in Vitro ; Humans ; In vitro fertilization ; Infant, Newborn ; Infertility ; Infertility - epidemiology ; Infertility - therapy ; Insemination, Artificial ; Medicine ; Morphology ; Normal distribution ; Original ; Ovaries ; Population ; Pregnancy ; Pregnancy Rate ; Reproductive health ; Retrospective Studies ; School dropouts ; Sexual intercourse</subject><ispartof>JBRA assisted reproduction, 2022-01, Vol.26 (1), p.22-27</ispartof><rights>2022. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-c6ceb3db8b9fcaff8583f9b554dbff0171d5134e97c4707d18cc5f21a9d321b93</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769183/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769183/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27928,27929,53795,53797</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34415121$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mendieta, Maitane Alonso de</creatorcontrib><creatorcontrib>Aranda, Alejandro Sánchez</creatorcontrib><creatorcontrib>López, Juan Francisco Molina</creatorcontrib><creatorcontrib>Sánchez, Armando Miguel Roque</creatorcontrib><creatorcontrib>Mondragón, Esperanza Carballo</creatorcontrib><creatorcontrib>Monterrosas, Leonor Ángela Durán</creatorcontrib><creatorcontrib>Ambe, Alberto Kably</creatorcontrib><title>Comparative analysis of the pregnancy rate via in vitro fertilization vs. previous artificial insemination in patients with unexplained infertility</title><title>JBRA assisted reproduction</title><addtitle>JBRA Assist Reprod</addtitle><description>To compare the clinical pregnancy rate among patients undergoing direct in vitro fertilization vs. in vitro fertilization after two cycles of intrauterine insemination in couples with unexplained infertility.
Comparative cross-sectional, retrospective study from 2016 to 2019, from the Centro Mexicano de Fertilidad Doctor Alberto Kably. The patients with unexplained infertility were divided into two groups, direct in vitro fertilization and a group of in vitro fertilization after intrauterine insemination, and we compared the rate of pregnancy and live births in both cases.
89 couples with unexplained infertility were included, the in vitro fertilization after intrauterine insemination group (n=46) and direct in vitro fertilization group (n=43). The direct in vitro fertilization group resulted in a higher clinical pregnancy rate throughout the study compared to the other group (55.8% vs. 34.8%, OR 2.37; 95% CI 1.008 - 5.57, p=0.046). However, there was no difference in the rate of live newborns (p=0.12). When analyzing the data by cycle, we noticed a statistical difference in both, the clinical pregnancy rate in the direct in vitro fertilization group (38.7% vs. 16.7%, OR 3.2; 95% CI 1.50-6.62), as well as the rate of live newborns (32.3 % vs. 14.6%, OR 2.79; 95% CI 1.28-6.07, p=0.008).
In the in vitro fertilization group, as first-line treatment for unexplained infertility, the patients had a higher pregnancy rate.</description><subject>Age</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Fertility</subject><subject>Fertilization in Vitro</subject><subject>Humans</subject><subject>In vitro fertilization</subject><subject>Infant, Newborn</subject><subject>Infertility</subject><subject>Infertility - epidemiology</subject><subject>Infertility - therapy</subject><subject>Insemination, Artificial</subject><subject>Medicine</subject><subject>Morphology</subject><subject>Normal distribution</subject><subject>Original</subject><subject>Ovaries</subject><subject>Population</subject><subject>Pregnancy</subject><subject>Pregnancy Rate</subject><subject>Reproductive health</subject><subject>Retrospective Studies</subject><subject>School dropouts</subject><subject>Sexual intercourse</subject><issn>1518-0557</issn><issn>1517-5693</issn><issn>1518-0557</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkc9OGzEQxi1EVRDwAj0gS71wSeo_6-z6UqmKoK2E1As9W16vTYx27a3tDYTX4IU7aUIEPc3I3-8bjedD6BMlcyG5-EIFbWZEiHrOCKOE8OYInR4ej9_0J-gi5wdCCJWU8Yp8RCe8qkBm9BS9LOMw6qSLX1usg-432WccHS4ri8dk74MOZoMBsHjtNfYBSkkRO5uK7_0zOCO85fmWXvs4ZaxBcd543QOe7eDDDgLvCJ0NJeNHX1Z4CvZp7LUPtgNxP7FsztEHp_tsL_b1DP2-ub5b_pjd_vr-c_ntdmYqTsrMLIxtedc2rXRGO9eIhjvZClF1rXOE1rQTlFdW1qaqSd3RxhjhGNWy44y2kp-hr7u549QOtjOwWNK9GpMfdNqoqL16rwS_UvdxrZp6IWnDYcDVfkCKfyabixp8NrbvdbBwCMXEgleMk3_o5__QhzgluDdQC8akYJAIUGxHmRRzTtYdlqFEbWNX21TVNlX1GjuYLt9-42B5DZn_BcsHrRE</recordid><startdate>20220101</startdate><enddate>20220101</enddate><creator>Mendieta, Maitane Alonso de</creator><creator>Aranda, Alejandro Sánchez</creator><creator>López, Juan Francisco Molina</creator><creator>Sánchez, Armando Miguel Roque</creator><creator>Mondragón, Esperanza Carballo</creator><creator>Monterrosas, Leonor Ángela Durán</creator><creator>Ambe, Alberto Kably</creator><general>Sociedade Brasileira de Reprodução Humana (Brazilian Society of Assisted Reproduction)</general><general>Brazilian Society of Assisted Reproduction</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220101</creationdate><title>Comparative analysis of the pregnancy rate via in vitro fertilization vs. previous artificial insemination in patients with unexplained infertility</title><author>Mendieta, Maitane Alonso de ; Aranda, Alejandro Sánchez ; López, Juan Francisco Molina ; Sánchez, Armando Miguel Roque ; Mondragón, Esperanza Carballo ; Monterrosas, Leonor Ángela Durán ; Ambe, Alberto Kably</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-c6ceb3db8b9fcaff8583f9b554dbff0171d5134e97c4707d18cc5f21a9d321b93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Age</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Fertility</topic><topic>Fertilization in Vitro</topic><topic>Humans</topic><topic>In vitro fertilization</topic><topic>Infant, Newborn</topic><topic>Infertility</topic><topic>Infertility - epidemiology</topic><topic>Infertility - therapy</topic><topic>Insemination, Artificial</topic><topic>Medicine</topic><topic>Morphology</topic><topic>Normal distribution</topic><topic>Original</topic><topic>Ovaries</topic><topic>Population</topic><topic>Pregnancy</topic><topic>Pregnancy Rate</topic><topic>Reproductive health</topic><topic>Retrospective Studies</topic><topic>School dropouts</topic><topic>Sexual intercourse</topic><toplevel>online_resources</toplevel><creatorcontrib>Mendieta, Maitane Alonso de</creatorcontrib><creatorcontrib>Aranda, Alejandro Sánchez</creatorcontrib><creatorcontrib>López, Juan Francisco Molina</creatorcontrib><creatorcontrib>Sánchez, Armando Miguel Roque</creatorcontrib><creatorcontrib>Mondragón, Esperanza Carballo</creatorcontrib><creatorcontrib>Monterrosas, Leonor Ángela Durán</creatorcontrib><creatorcontrib>Ambe, Alberto Kably</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>JBRA assisted reproduction</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mendieta, Maitane Alonso de</au><au>Aranda, Alejandro Sánchez</au><au>López, Juan Francisco Molina</au><au>Sánchez, Armando Miguel Roque</au><au>Mondragón, Esperanza Carballo</au><au>Monterrosas, Leonor Ángela Durán</au><au>Ambe, Alberto Kably</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative analysis of the pregnancy rate via in vitro fertilization vs. previous artificial insemination in patients with unexplained infertility</atitle><jtitle>JBRA assisted reproduction</jtitle><addtitle>JBRA Assist Reprod</addtitle><date>2022-01-01</date><risdate>2022</risdate><volume>26</volume><issue>1</issue><spage>22</spage><epage>27</epage><pages>22-27</pages><issn>1518-0557</issn><issn>1517-5693</issn><eissn>1518-0557</eissn><abstract>To compare the clinical pregnancy rate among patients undergoing direct in vitro fertilization vs. in vitro fertilization after two cycles of intrauterine insemination in couples with unexplained infertility.
Comparative cross-sectional, retrospective study from 2016 to 2019, from the Centro Mexicano de Fertilidad Doctor Alberto Kably. The patients with unexplained infertility were divided into two groups, direct in vitro fertilization and a group of in vitro fertilization after intrauterine insemination, and we compared the rate of pregnancy and live births in both cases.
89 couples with unexplained infertility were included, the in vitro fertilization after intrauterine insemination group (n=46) and direct in vitro fertilization group (n=43). The direct in vitro fertilization group resulted in a higher clinical pregnancy rate throughout the study compared to the other group (55.8% vs. 34.8%, OR 2.37; 95% CI 1.008 - 5.57, p=0.046). However, there was no difference in the rate of live newborns (p=0.12). When analyzing the data by cycle, we noticed a statistical difference in both, the clinical pregnancy rate in the direct in vitro fertilization group (38.7% vs. 16.7%, OR 3.2; 95% CI 1.50-6.62), as well as the rate of live newborns (32.3 % vs. 14.6%, OR 2.79; 95% CI 1.28-6.07, p=0.008).
In the in vitro fertilization group, as first-line treatment for unexplained infertility, the patients had a higher pregnancy rate.</abstract><cop>Brazil</cop><pub>Sociedade Brasileira de Reprodução Humana (Brazilian Society of Assisted Reproduction)</pub><pmid>34415121</pmid><doi>10.5935/1518-0557.20210038</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Age Cross-Sectional Studies Female Fertility Fertilization in Vitro Humans In vitro fertilization Infant, Newborn Infertility Infertility - epidemiology Infertility - therapy Insemination, Artificial Medicine Morphology Normal distribution Original Ovaries Population Pregnancy Pregnancy Rate Reproductive health Retrospective Studies School dropouts Sexual intercourse |
| title | Comparative analysis of the pregnancy rate via in vitro fertilization vs. previous artificial insemination in patients with unexplained infertility |
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