Cyclohexyl-griselimycin Is Active against Mycobacterium abscessus in Mice

Cyclohexyl-griselimycin is a preclinical candidate for use against tuberculosis (TB). Here, we show that this oral cyclodepsipeptide is also active against the intrinsically drug-resistant nontuberculous mycobacterium Mycobacterium abscessus and in a mouse model of infection. This adds a novel advan...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2022-01, Vol.66 (1), p.e0140021-e0140021
Hauptverfasser:	Aragaw, Wassihun Wedajo, Roubert, Christine, Fontaine, Evelyne, Lagrange, Sophie, Zimmerman, Matthew D, Dartois, Véronique, Gengenbacher, Martin, Dick, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimicrobial Chemotherapy Editor's Pick Experimental Therapeutics
Online-Zugang:	Volltext
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