Potency and Preclinical Evidence of Synergy of Oral Azole Drugs and Miltefosine in an Ex Vivo Model of Leishmania ( Viannia ) panamensis Infection

Failure of treatment of cutaneous leishmaniasis with antimonial drugs and miltefosine is frequent. Use of oral combination therapy represents an attractive strategy to increase efficacy of treatment and reduce the risk of drug resistance. We evaluated the potency of posaconazole, itraconazole, voric...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Antimicrobial agents and chemotherapy 2022-01, Vol.66 (1), p.e0142521
Hauptverfasser:	Fernández, Olga Lucía, Rosales-Chilama, Mariana, Quintero, Natali, Travi, Bruno L, Wetzel, Dawn M, Gómez, María Adelaida, Saravia, Nancy Gore
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimicrobial Chemotherapy Editor's Pick Experimental Therapeutics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!